BNIP3L/NIX Antikörper (Middle Region)

Produktnummer ABIN2787863

Produktdetails anti-BNIP3L/NIX Antikörper

Target: BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BNIP3L/NIX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: CDSPSPQEDG QIMFDVEMHT SRDHSSQSEE EVVEGEKEVE ALKKSADWVS

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Bnip3l. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 218 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu BNIP3L/NIX

Target: BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))

Andere Bezeichnung: Bnip3l (BNIP3L Produkte)

Synonyme: BNIP3a antikoerper, NIX antikoerper, NIP3 antikoerper, Nix antikoerper, Nip3 antikoerper, C86132 antikoerper, D14Ertd719e antikoerper, Nip3L antikoerper, bnip3l antikoerper, nip3 antikoerper, zgc:110478 antikoerper, bnip3l2 antikoerper, wu:fb52b03 antikoerper, wu:fc02h04 antikoerper, BCL2 interacting protein 3 like antikoerper, BCL2 interacting protein 3 antikoerper, BCL2/adenovirus E1B interacting protein 3 antikoerper, BCL2/adenovirus E1B interacting protein 3-like antikoerper, BCL2/adenovirus E1B interacting protein 3-like b antikoerper, BCL2/adenovirus E1B interacting protein 3-like a antikoerper, BNIP3L antikoerper, BNIP3 antikoerper, Bnip3l antikoerper, Bnip3 antikoerper, bnip3lb antikoerper, bnip3la antikoerper

Hintergrund: Bnip3l induces apoptosis. It interacts with viral and cellular anti-apoptosis proteins. It can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. It inhibits apoptosis induced by BNIP3. It is involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. Bnip3l may function as a tumor suppressor.
Alias Symbols: C86132, D14Ertd719e, Nip3L, Nix
Protein Size: 218

Molekulargewicht: 24 kDa

Gen-ID: 12177

NCBI Accession: NM_009761, NP_033891

UniProt: Q9Z2F7

Pathways: Autophagie