TINF2 Antikörper (Middle Region)

Produktnummer ABIN2787641

Produktdetails anti-TINF2 Antikörper

Target: TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Rind (Kuh), Hund, Schwein, Ratte, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TINF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SDEEENGQGE GKESLENYQK TKFDTLIPTL CEYLPPSGHG AIPVSSCDCR

Homologie: Cow: 100%, Dog: 86%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 100%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against TINF2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TINF2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 451 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TINF2

Target: TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))

Andere Bezeichnung: TINF2 (TIN2 Produkte)

Synonyme: DKCA3 antikoerper, TIN2 antikoerper, AW552114 antikoerper, D14Wsu146e antikoerper, Tin2 antikoerper, TERF1 interacting nuclear factor 2 antikoerper, Terf1 (TRF1)-interacting nuclear factor 2 antikoerper, TINF2 antikoerper, Tinf2 antikoerper

Hintergrund: TINF2 is a component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends, without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. It plays a role in shelterin complex assembly.
Alias Symbols: TIN2, DKCA3
Protein Interaction Partner: ACD, TERF2, TPP1, ANXA8L1, TNKS, TERF1, VIPR1, ZNF790, PAGE2, TUBB, DHFRL1, APOBEC3F, REM2, NUDCD2, CCDC43, SCRN2, TRIM15, TXNDC17, AFAP1L2, FERMT3, KCTD17, ANKMY2, PPP6R3, PGM2, APPL2, BIN2, LGALSL, PHPT1, GNMT, OR2H1, CCDC9, POT1, AIPL1, NCDN, ACOT7, TO
Protein Size: 451

Molekulargewicht: 50 kDa

Gen-ID: 26277

NCBI Accession: NM_001099274, NP_001092744

UniProt: Q9BSI4

Pathways: Zellzyklus, Telomere Maintenance, Regulation of Carbohydrate Metabolic Process