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PSMD4/ASF Antikörper (N-Term)

Psmd4 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schaf, Kaninchen, Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Saccharomyces cerevisiae WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2787532
  • Target Alle PSMD4/ASF (Psmd4) Antikörper anzeigen
    PSMD4/ASF (Psmd4) (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))
    Bindungsspezifität
    • 18
    • 14
    • 7
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 64
    • 19
    • 18
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    Human, Maus, Ratte, Rind (Kuh), Schaf, Kaninchen, Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Saccharomyces cerevisiae
    Wirt
    • 58
    • 6
    • 1
    • 1
    Kaninchen
    Klonalität
    • 60
    • 6
    Polyklonal
    Konjugat
    • 36
    • 6
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PSMD4/ASF Antikörper ist unkonjugiert
    Applikation
    • 56
    • 38
    • 21
    • 8
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    VLESTMVCVD NSEYMRNGDF LPTRLQAQQD AVNIVCHSKT RSNPENNVGL
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 92%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against PSMD4. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human PSMD4
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    Discover our top product Psmd4 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 377 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ghi, Di Brisco, Dallorto, Osella, Orsetti: "Age-related modifications of egr1 expression and ubiquitin-proteasome components in pet dog hippocampus." in: Mechanisms of ageing and development, Vol. 130, Issue 5, pp. 320-7, (2009) (PubMed).

  • Target
    PSMD4/ASF (Psmd4) (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))
    Andere Bezeichnung
    PSMD4 (Psmd4 Produkte)
    Synonyme
    af-1 antikoerper, mcb1 antikoerper, pub-r5 antikoerper, rpn10 antikoerper, PSMD4 antikoerper, DDBDRAFT_0202512 antikoerper, DDBDRAFT_0232981 antikoerper, DDB_0202512 antikoerper, DDB_0232981 antikoerper, AF antikoerper, AF-1 antikoerper, ASF antikoerper, MCB1 antikoerper, Rpn10 antikoerper, S5A antikoerper, pUB-R5 antikoerper, xrpn10c antikoerper, Af1 antikoerper, Mcb1 antikoerper, angiocidin antikoerper, im:6912672 antikoerper, psmd4 antikoerper, wu:fc68c04 antikoerper, zgc:110247 antikoerper, proteasome 26S subunit, non-ATPase 4 antikoerper, 26S proteasome non-ATPase regulatory subunit 4 antikoerper, 26s proteasome non-atpase regulatory subunit 4 (26s proteasomeregulatory subunit s5a) antikoerper, proteasome 26S subunit, non-ATPase 4 L homeolog antikoerper, proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 antikoerper, proteasome 26S subunit, non-ATPase 4b antikoerper, psmd4 antikoerper, PSMD4 antikoerper, LOC100194679 antikoerper, psmD4 antikoerper, LOC100283637 antikoerper, Smp_000740.1 antikoerper, psmd4.L antikoerper, Psmd4 antikoerper, psmd4b antikoerper
    Hintergrund
    The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD4 encodes one of the non-ATPase subunits of the 19S regulator lid. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. Pseudogenes have been identified on chromosomes 10 and 21. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: AF, AF-1, ASF, MCB1, Rpn10, S5A, pUB-R5
    Protein Interaction Partner: UBC, cdc20, XPC, SPRTN, PSMD14, MDM2, PSMC2, PSMA1, ADRM1, UBQLN1, TXNL1, PSMD3, PSMD2, PSMD1, PSMC6, PSMC4, PSMC1, UCHL5, RPS12, PSMD8, UBQLN4, VCP, GJA1, DIO2, SCHIP1, FBXO6, PARK2, UL76, FBXO25, LOC100044627, Gm4705, LOC677113, Rps6-ps4, Rpl34-ps1, Rpl
    Protein Size: 377
    Molekulargewicht
    41 kDa
    Gen-ID
    5710
    NCBI Accession
    NM_002810, NP_002801
    UniProt
    P55036
    Pathways
    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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