PCSK6 Antikörper (N-Term)

Produktnummer ABIN2787440

Produktdetails anti-PCSK6 Antikörper

Target: PCSK6 (Proprotein Convertase Subtilisin/kexin Type 6 (PCSK6))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Kaninchen, Maus, Rind (Kuh), Hund, Pferd, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCSK6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: NYDSYASYDV NGNDYDPSPR YDASNENKHG TRCAGEVAAS ANNSYCIVGI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against PCSK6. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PCSK6

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 975 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PCSK6

Target: PCSK6 (Proprotein Convertase Subtilisin/kexin Type 6 (PCSK6))

Andere Bezeichnung: PCSK6 (PCSK6 Produkte)

Synonyme: PACE4 antikoerper, PCSK6 antikoerper, SPC4 antikoerper, C86343 antikoerper, Pace4 antikoerper, Spc4 antikoerper, PACE4AIIa antikoerper, Xpace4 antikoerper, spc4 antikoerper, proprotein convertase subtilisin/kexin type 6 antikoerper, peptidase S8 antikoerper, proprotein convertase subtilisin/kexin type 6 L homeolog antikoerper, PCSK6 antikoerper, EAMY_RS27925 antikoerper, pcsk6 antikoerper, Pcsk6 antikoerper, pcsk6.L antikoerper

Hintergrund: PCSK6 is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. This gene is thought to play a role in tumor progression.The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: PACE4, SPC4
Protein Interaction Partner: env, UBC, CACNA1A, RCN3, FLG, PMCH, PCSK6,
Protein Size: 975

Molekulargewicht: 91 kDa

Gen-ID: 5046

NCBI Accession: NM_138320, NP_612193

UniProt: Q63415

Pathways: Neurotrophin Signalübertragung, SARS-CoV-2 Protein Interaktom