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PKM2 Antikörper (N-Term)

PKM2 Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2787393
  • Target Alle PKM2 Antikörper anzeigen
    PKM2 (Pyruvate Kinase M2 (PKM2))
    Bindungsspezifität
    • 17
    • 16
    • 16
    • 15
    • 11
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 157
    • 100
    • 87
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd
    Wirt
    • 134
    • 22
    • 5
    • 1
    Kaninchen
    Klonalität
    • 140
    • 22
    Polyklonal
    Konjugat
    • 60
    • 15
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser PKM2 Antikörper ist unkonjugiert
    Applikation
    • 98
    • 46
    • 27
    • 27
    • 24
    • 24
    • 19
    • 17
    • 10
    • 7
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    MSKPHSEAGT AFIQTQQLHA AMADTFLEHM CRLDIDSPPI TARNTGIICT
    Homologie
    Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against PKM2. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human PKM2
    Top Product
    Discover our top product PKM2 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 531 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    PKM2 (Pyruvate Kinase M2 (PKM2))
    Andere Bezeichnung
    PKM2 (PKM2 Produkte)
    Synonyme
    CTHBP antikoerper, OIP3 antikoerper, PK3 antikoerper, PKM2 antikoerper, TCB antikoerper, THBP1 antikoerper, AA414905 antikoerper, AL024370 antikoerper, AL024424 antikoerper, Pk-2 antikoerper, Pk-3 antikoerper, Pk3 antikoerper, Pkm2 antikoerper, PKM12 antikoerper, PKM antikoerper, pyruvate kinase M1/2 antikoerper, pyruvate kinase, muscle antikoerper, PKM antikoerper, Pkm antikoerper
    Hintergrund
    This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported.
    Alias Symbols: CTHBP, MGC3932, OIP3, PK3, PKM, TCB, THBP1, PKM2
    Protein Interaction Partner: LNX1, NXT2, HUWE1, ISG15, UBC, POLE2, FUS, SUMO2, SUMO3, STAU1, MDM2, SUZ12, EZH2, IPO11, TWF2, PDLIM5, NPLOC4, PLIN3, UBA2, EIF4A3, ANP32A, SRP14, RAD23B, PPP1CA, PIN1, CTPS1, CBS, CAPZA2, ACAT2, NLK, FBXO6, YWHAQ, RAF1, IGSF8, HDAC6, MAPK7, NPM1, CDK2,
    Protein Size: 531
    Molekulargewicht
    58 kDa
    Gen-ID
    5315
    NCBI Accession
    NM_002654, NP_002645
    UniProt
    P14618
    Pathways
    Warburg Effekt
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