RAD1 Antikörper (Middle Region)

Produktnummer ABIN2787356

Produktdetails anti-RAD1 Antikörper

Target: RAD1 (Cell Cycle Checkpoint Protein RAD1 (RAD1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Pferd, Kaninchen, Rind (Kuh), Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ITMSPDKPYF RLSTFGNAGS SHLDYPKDSD LMEAFHCNQT QVNRYKISLL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RAD1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RAD1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 282 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RAD1

Target: RAD1 (Cell Cycle Checkpoint Protein RAD1 (RAD1))

Andere Bezeichnung: RAD1 (RAD1 Produkte)

Synonyme: HRAD1 antikoerper, REC1 antikoerper, zgc:56502 antikoerper, zgc:77779 antikoerper, RAD1 antikoerper, xrad1 antikoerper, DKFZp459H1127 antikoerper, RAD1 checkpoint DNA exonuclease antikoerper, RAD1 homolog (S. pombe) antikoerper, RAD1 antikoerper, Rad1 antikoerper, rad1 antikoerper

Hintergrund: This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described.
Alias Symbols: HRAD1, REC1
Protein Interaction Partner: ATRX, FEN1, UBC, MSH3, MSH2, MSH6, COPS5, HUS1, ATR, MAP1LC3B, HUS1B, RAD9B, RAD17, POLB, DNAJC7, PARK2, RPA2, RPA1, RAD9A,
Protein Size: 282

Molekulargewicht: 32 kDa

Gen-ID: 5810

NCBI Accession: NM_002853, NP_002844

UniProt: O60671

Pathways: M Phase