Pellino 1 Antikörper (N-Term)

Produktnummer ABIN2787222

Produktdetails anti-Pellino 1 Antikörper

Target: Pellino 1 (PELI1) (Pellino E3 Ubiquitin Protein Ligase 1 (PELI1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Zebrafisch (Danio rerio), Hund, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Pellino 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ESPIDFVVTD TVPGSQSNSD TQSVQSTISR FACRIICERN PPFTARIYAA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PELI1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PELI1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 418 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Pellino 1

Target: Pellino 1 (PELI1) (Pellino E3 Ubiquitin Protein Ligase 1 (PELI1))

Andere Bezeichnung: PELI1 (PELI1 Produkte)

Synonyme: 2810468L03Rik antikoerper, A930031K15Rik antikoerper, AA409794 antikoerper, AI586297 antikoerper, D11Ertd676e antikoerper, peli1 antikoerper, peli1.L antikoerper, pellino1 antikoerper, xpellino1 antikoerper, wu:fd12d01 antikoerper, zgc:153297 antikoerper, pellino E3 ubiquitin protein ligase 1 antikoerper, pellino 1 antikoerper, pellino E3 ubiquitin protein ligase 1 S homeolog antikoerper, pellino E3 ubiquitin protein ligase 1b antikoerper, PELI1 antikoerper, Peli1 antikoerper, peli1.S antikoerper, peli1b antikoerper

Hintergrund: PELI1 is an scaffold protein involved in the IL-1 signaling pathway via its interaction with the complex containing IRAK kinases and TRAF6. PELI1 is required for NF-kappa-B activation and IL-8 gene expression in response to IL-1.
Alias Symbols: DKFZp686C18116, MGC50990
Protein Interaction Partner: UBC, VAC14, TRIP13, BCL6, SRPK2, SRPK1, DEAF1, IRAK1, UBE2V1, UBE2N, UBE2D2, UBE2D1, IRAK4, TRAF6, NR2C2, MYD88, SMAD6, IL1R1, TBK1, IKBKB, UBE2I, RIPK1, IRAK2,
Protein Size: 418

Molekulargewicht: 46 kDa

Gen-ID: 57162

NCBI Accession: NM_020651, NP_065702

UniProt: Q8C669

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades