PI4K2B Antikörper (N-Term)

Produktnummer ABIN2787116

Produktdetails anti-PI4K2B Antikörper

Target: PI4K2B (Phosphatidylinositol 4-Kinase Type 2 beta (PI4K2B))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Rind (Kuh), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PI4K2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EDPEFADIVL KAEQAIEIGV FPERISQGSS GSYFVKDSKR NIIGVFKPKS

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Pi4k2b. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 469 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PI4K2B

Target: PI4K2B (Phosphatidylinositol 4-Kinase Type 2 beta (PI4K2B))

Andere Bezeichnung: Pi4k2b (PI4K2B Produkte)

Synonyme: GB16449 antikoerper, pi4kiib antikoerper, pik42b antikoerper, PI4KIIB antikoerper, PIK42B antikoerper, 2610042N09Rik antikoerper, 4933409G22Rik antikoerper, zgc:158305 antikoerper, uncharacterized LOC725812 antikoerper, phosphatidylinositol 4-kinase type 2 beta L homeolog antikoerper, phosphatidylinositol 4-kinase type 2 beta antikoerper, LOC725812 antikoerper, pi4k2b.L antikoerper, PI4K2B antikoerper, pi4k2b antikoerper, Pi4k2b antikoerper

Hintergrund: Together with PI4K2A and the type III PI4Ks (PIK4CA and PIK4CB) Pi4k2b contributes to the overall PI4-kinase activity of the cell. This contribution may be especially significant in plasma membrane, endosomal and Golgi compartments. The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3). Pi4k2b contributes to the production of InsP3 in stimulated cells and is likely to be involved in the regulation of vesicular trafficking.
Alias Symbols: 2610042N09Rik, 4933409G22Rik
Protein Size: 469

Molekulargewicht: 52 kDa

Gen-ID: 67073

NCBI Accession: NM_025951, NP_080227

UniProt: Q8CBQ5

Pathways: Inositol Metabolic Process