ERCC6L Antikörper (N-Term)

Produktnummer ABIN2787014

Produktdetails anti-ERCC6L Antikörper

Target: ERCC6L (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Pferd, Rind (Kuh), Hund, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERCC6L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GDLEEAFKLF NLAKDIFPNE KVLSRIQKIQ EALEELAEQG DDEFTDVCNS

Homologie: Cow: 93%, Dog: 93%, Horse: 86%, Human: 100%, Pig: 86%, Rabbit: 93%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against ERCC6L. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ERCC6L

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1250 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ERCC6L

Target: ERCC6L (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L))

Andere Bezeichnung: ERCC6L (ERCC6L Produkte)

Synonyme: PICH antikoerper, RAD26L antikoerper, BC004701 antikoerper, D330021P09Rik antikoerper, RGD1565734 antikoerper, fc22h03 antikoerper, si:ch211-278b8.3 antikoerper, wu:fc22h03 antikoerper, ERCC excision repair 6 like, spindle assembly checkpoint helicase antikoerper, excision repair cross-complementing rodent repair deficiency complementation group 6 like antikoerper, DNA excision repair protein ERCC-6-like antikoerper, excision repair cross-complementation group 6-like antikoerper, ERCC6L antikoerper, Ercc6l antikoerper, LOC100373376 antikoerper, LOC100494766 antikoerper, LOC100552957 antikoerper, LOC100560751 antikoerper, LOC100563247 antikoerper, ercc6l antikoerper

Hintergrund: ERCC6L is a DNA helicase that acts as an essential component of the spindle assembly checkpoint.ERCC6L contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. ERCC6L acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.
Alias Symbols: FLJ20105, MGC131695, PICH
Protein Interaction Partner: LMO4, UBC, HTT, BARD1, ACACA, Ercc6l, Plk1, RB1CC1, RPA3,
Protein Size: 1250

Molekulargewicht: 141 kDa

Gen-ID: 54821

NCBI Accession: NM_017669, NP_060139

UniProt: Q2NKX8