SHC3 Antikörper (N-Term)

Produktnummer ABIN2786991

Produktdetails anti-SHC3 Antikörper

Target: SHC3 (SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SHC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PSKMLSSILG KSNLQFAGMS ISLTISTASL NLRTPDSKQI IANHHMRSIS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against Shc3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 474 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SHC3

Target: SHC3 (SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3))

Andere Bezeichnung: Shc3 (SHC3 Produkte)

Synonyme: N-Shc antikoerper, NSHC antikoerper, RAI antikoerper, SHCC antikoerper, ShcC antikoerper, Rai antikoerper, SHC adaptor protein 3 antikoerper, src homology 2 domain-containing transforming protein C3 antikoerper, SHC3 antikoerper, Shc3 antikoerper

Hintergrund: Shc3 is a signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. It is involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
Alias Symbols: MGC124163, N-Shc, Rai, ShcC
Protein Interaction Partner: Src, Grin2b, Grin1, Axl, Egfr, Ntrk1,
Protein Size: 474

Molekulargewicht: 52 kDa

Gen-ID: 20418

NCBI Accession: NM_009167, NP_033193

UniProt: Q61120

Pathways: RTK Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung