SGK1 Antikörper (serum/glucocorticoid Regulated Kinase 1) (N-Term)

Details for Product anti-SGK1 Antibody No. ABIN2786820, Anbieter: Anmelden zum Anzeigen
Antigen
  • SGK
  • Sgk
  • cb1083
  • sgk
  • wu:fc20a09
  • serum/glucocorticoid regulated kinase 1
  • SGK1
  • Sgk1
  • sgk1
Epitop
N-Term
46
28
27
17
15
15
15
12
11
7
4
4
4
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch (Danio rerio)
242
129
120
13
9
9
7
6
4
3
3
2
2
1
1
Wirt
Kaninchen
189
38
12
5
Klonalität
Polyklonal
Konjugat
Dieser SGK1 Antikörper ist unkonjugiert
8
8
7
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
187
118
94
58
50
39
18
10
7
5
5
4
2
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human SGK1
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN983673.
Sequenz ANPSPPPSPS QQINLGPSSN PHAKPSDFHF LKVIGKGSFG KVLLARHKAE
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
Produktmerkmale This is a rabbit polyclonal antibody against SGK1. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Plasmids, Primers & others Plasmide, Primers & weitere SGK1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung SGK1 (SGK1 Antibody Abstract)
Hintergrund This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell sur
Alias Symbols: SGK
Protein Interaction Partner: AKT1S1, YWHAQ, YWHAZ, MAPT, MTOR, CDKN1B, RPTOR, NEDD4L, Tmem109, Rabac1, GADD45G, UBC, MAGEA1, HSP90AA1, TMEM184C, WNK1, WNK2, WNK4, RAF1, PDPK1, NEDD4, TSC22D3, STUB1, HSPA4, ELAVL1, COMMD1, SYVN1, SCNN1B, RICTOR, PDK1, YPK1, IKBKG, CAMKK1, KCNJ1, GSK3A
Protein Size: 431
Molekulargewicht 49 kDa
Gen-ID 6446
NCBI Accession NM_005627, NP_005618
UniProt O00141
Pathways MAPK Signalweg, Notch Signalweg, Steroid Hormone Mediated Signaling Pathway
Applikations-hinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 431 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (N-Term) antibody (ABIN2786820) WB Suggested Anti-SGK1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...
Western Blotting (WB) image for anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (N-Term) antibody (ABIN2786820) WB Suggested Anti-SGK1
Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <...
Allgemeine Veröffentlichungen Pew, Zou, Brickley, Conzen: "Glucocorticoid (GC)-mediated down-regulation of urokinase plasminogen activator expression via the serum and GC regulated kinase-1/forkhead box O3a pathway." in: Endocrinology, Vol. 149, Issue 5, pp. 2637-45, 2008 (PubMed).

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