RFC1 Antikörper (Middle Region)

Produktnummer ABIN2786753

Produktdetails anti-RFC1 Antikörper

Target: RFC1 (Replication Factor C (Activator 1) 1, 145kDa (RFC1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Kaninchen, Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RFC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AQAIYASVLP GELMRGYMTQ FPTFPSWLGK HSSTGKHDRI VQDLALHMSL

Homologie: Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against RFC1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RFC1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1147 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RFC1

Target: RFC1 (Replication Factor C (Activator 1) 1, 145kDa (RFC1))

Andere Bezeichnung: RFC1 (RFC1 Produkte)

Synonyme: A1 antikoerper, MHCBFB antikoerper, PO-GA antikoerper, RECC1 antikoerper, RFC antikoerper, RFC140 antikoerper, AtRFC1 antikoerper, replication factor C 1 antikoerper, replication factor C1 antikoerper, 140kDa antikoerper, Alp145 antikoerper, Recc1 antikoerper, Replication factor C1 antikoerper, si:dkey-170e5.1 antikoerper, zgc:162875 antikoerper, replication factor C subunit 1 antikoerper, replication factor C1 antikoerper, replication factor C (activator 1) 1 antikoerper, DNA replication factor C complex subunit Rfc1 antikoerper, RFC1 antikoerper, Rfc1 antikoerper, rfc1 antikoerper

Hintergrund: The protein encoded by this gene is the large subunit of replication factor C, which is a five subunit DNA polymerase accessory protein. Replication factor C is a DNA-dependent ATPase that is required for eukaryotic DNA replication and repair. The protein acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It also may have a role in telomere stability.
Alias Symbols: A1, MGC51786, MHCBFB, PO-GA, RECC1, RFC, RFC140
Protein Interaction Partner: SPRTN, UBC, PCNA, RPA3, RPA2, RPA1, YWHAQ, SMC1A, RFC4, NOTCH1, WDR18, RBM14, RFC5, RFC3, RFC2, LAMP2, MYOC, SIRT7, SUMO2, HDGF, RAD17, CSNK2B, tat, SAP25, ZSCAN1, SSBP3, PMS1, CEBPA, BRCA1, RFC1, BRD4, HDAC1, CASP3, TCEAL1, CCND1, RELA, CDK4, CHTF18, SMA
Protein Size: 1147

Molekulargewicht: 128 kDa

Gen-ID: 5981

NCBI Accession: NM_002913, NP_002904

Pathways: Telomere Maintenance, DNA Reparatur, DNA Replication, Synthesis of DNA, Dicarboxylic Acid Transport