PSMB2 Antikörper (Middle Region)

Produktnummer ABIN2786715

Produktdetails anti-PSMB2 Antikörper

Target: PSMB2 (Proteasome (Prosome, Macropain) Subunit, beta Type 2 (PSMB2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: YDEHEGPALY YMDYLAALAK APFAAHGYGA FLTLSILDRY YTPTISRERA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PSMB2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PSMB2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 201 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PSMB2

Target: PSMB2 (Proteasome (Prosome, Macropain) Subunit, beta Type 2 (PSMB2))

Andere Bezeichnung: PSMB2 (PSMB2 Produkte)

Synonyme: HC7-I antikoerper, 19.m02268 antikoerper, DDBDRAFT_0190287 antikoerper, DDBDRAFT_0232958 antikoerper, DDB_0190287 antikoerper, DDB_0232958 antikoerper, Psmb2 antikoerper, ACYPI004276 antikoerper, AU045357 antikoerper, AW108089 antikoerper, C7-I antikoerper, D4Wsu33e antikoerper, zgc:92282 antikoerper, proteasome subunit beta 2 antikoerper, proteasome subunit beta type 2 antikoerper, proteasome beta 2 subunit antikoerper, putative proteasome beta 2 subunit antikoerper, 20S proteasome subunit beta-2 antikoerper, proteasome (prosome, macropain) subunit, beta type 2 antikoerper, proteasome subunit beta 2 L homeolog antikoerper, PSMB2 antikoerper, CNC04990 antikoerper, Tc00.1047053510287.30 antikoerper, Tc00.1047053503891.100 antikoerper, Tc00.1047053508461.430 antikoerper, LBRM_34_3820 antikoerper, LBRM_35_0400 antikoerper, BBOV_I004450 antikoerper, LMJF_36_0320 antikoerper, psmB2 antikoerper, Psmb2 antikoerper, psmb2 antikoerper, psmb2.L antikoerper

Hintergrund: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMB2 is a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HC7-I, MGC104215, MGC126885
Protein Interaction Partner: KCTD9, UBC, KRT13, PSMD14, ASB11, POMP, PSMB8, PSMB7, PSMB6, PSMB5, PYCRL, PSMB4, PSMB3, PSMB1, PSMA7, PSMA6, PSMA5, PSMA4, PSMA3, PSMA1, HOXA2, PSMA2, PARK2, CDK20, ITGA4, GPX2, FN1, DDX49, IQCB1, VCAM1, SULT1A4, TUBB, PSMA8, C11orf58, SEC23A, PSME3, PSM
Protein Size: 201

Molekulargewicht: 23 kDa

Gen-ID: 5690

NCBI Accession: NM_002794, NP_002785

UniProt: P49721

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA