Galectin 3 Antikörper (N-Term)

Produktnummer ABIN2785832

Produktdetails anti-Galectin 3 Antikörper

Target: Galectin 3 (LGALS3)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Schwein, Hund, Meerschweinchen, Pferd, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Galectin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: GASYPGAYPG QAPPGAYPGQ APPGAYPGAP GAYPGAPAPG VYPGPPSGPG

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against LGALS3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LGALS3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 250 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Galectin 3 Antikörper (ABIN2785832)

Guha, Bandyopadhyaya, Polumuri, Chumsri, Gade, Kalvakolanu, Ahmed et al.: "Nicotine promotes apoptosis resistance of breast cancer cells and enrichment of side population cells with cancer stem cell-like properties via a signaling cascade involving galectin-3, α9 nicotinic ..." in: Breast cancer research and treatment, Vol. 145, Issue 1, pp. 5-22, (2014) (PubMed).

Details zu Galectin 3

Target: Galectin 3 (LGALS3)

Andere Bezeichnung: LGALS3 (LGALS3 Produkte)

Synonyme: CBP 35 antikoerper, Gal-3 antikoerper, Galectin-3 antikoerper, leg3 antikoerper, galactoside-binding antikoerper, galectin-3 antikoerper, lectin antikoerper, soluble antikoerper, CBP35 antikoerper, GAL3 antikoerper, GALBP antikoerper, GALIG antikoerper, L31 antikoerper, LGALS2 antikoerper, MAC2 antikoerper, MGC52947 antikoerper, MGC75803 antikoerper, LGALS3 antikoerper, gal-3 antikoerper, GBP antikoerper, L-34 antikoerper, Mac-2 antikoerper, gal3 antikoerper, galectin 3 antikoerper, Galectin-3 antikoerper, avian beta-defensin 3 antikoerper, lectin, galactoside-binding, soluble, 3 L homeolog antikoerper, lectin, galactoside-binding, soluble, 3 antikoerper, galectin 2 antikoerper, lectin, galactose binding, soluble 3 antikoerper, LGALS3 antikoerper, leg3 antikoerper, AvBD3 antikoerper, lgals3.L antikoerper, lgals3 antikoerper, LGALS2 antikoerper, Lgals3 antikoerper

Substanzklasse: Chemical

Hintergrund: LGALS3 is a galactose-specific lectin which binds IgE. IT may mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, it is required for terminal differentiation of columnar epithelial cells during early embryogenesis.
Alias Symbols: CBP35, GAL3, GALBP, GALIG, LGALS2, MAC2, L31
Protein Interaction Partner: PRR13, SS18L1, PPIG, LGALS3, GOLGA2, MAP1LC3A, SQSTM1, RAB7A, LAMP1, EGFR, CFTR, PAXIP1, BARD1, AGPS, IGBP1, GTF2I, CLNS1A, APP, SLC25A5, ACTA1, MYOC, LGALS3BP, CYHR1, GEMIN4, SUFU, CUBN, CSNK1A1, LIM2, FCGR2A, ELN, MMP2, CSNK2A2, CSNK2A1, C1GALT1C1, LGAL
Protein Size: 250

Molekulargewicht: 26 kDa

Gen-ID: 3958

NCBI Accession: NM_002306, NP_002297

UniProt: P17931

Pathways: RTK Signalweg