ARG2 Antikörper (C-Term)
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- Target Alle ARG2 Antikörper anzeigen
- ARG2 (Arginase, Type II (ARG2))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Pferd, Kaninchen, Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ARG2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- SALDLVEVNP QLATSEEEAK TTANLAVDVI ASSFGQTREG GHIVYDQLPT
- Kreuzreaktivität
- Rind (Kuh), Hund, Human, Maus, Kaninchen, Ratte (Rattus)
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 87%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against ARG2. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human ARG2
- Top Product
- Discover our top product ARG2 Primärantikörper
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- Applikationshinweise
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WB Suggested Anti-ARG2 Antibody Titration: 0.2-1 µg/mL
Positive Control: Jurkat cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. - Kommentare
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Antigen size: 354 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Nicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109A expressed by immune cells." in: The Journal of clinical investigation, Vol. 121, Issue 3, pp. 1163-73, (2011) (PubMed).
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Nicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109A expressed by immune cells." in: The Journal of clinical investigation, Vol. 121, Issue 3, pp. 1163-73, (2011) (PubMed).
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- Target
- ARG2 (Arginase, Type II (ARG2))
- Andere Bezeichnung
- Arginase-2 (ARG2 Produkte)
- Synonyme
- AII antikoerper, AU022422 antikoerper, zgc:65793 antikoerper, zgc:85630 antikoerper, wu:fb67g02 antikoerper, ARG2 antikoerper, LeARG2 antikoerper, arg1 antikoerper, arg3 antikoerper, arg2 antikoerper, arg2-c antikoerper, arg2-b antikoerper, arginase 2 antikoerper, arginase type II antikoerper, arginase 2 L homeolog antikoerper, arginase 2 S homeolog antikoerper, ARG2 antikoerper, Arg2 antikoerper, arg2 antikoerper, arg2.L antikoerper, arg2.S antikoerper
- Hintergrund
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Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. ARG2 (type II isoform) is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood, it is thought to play a role in nitric oxide and polyamine metabolism.Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood, it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: UBC, ARG1,
Protein Size: 354 - Molekulargewicht
- 39 kDa
- Gen-ID
- 384
- NCBI Accession
- NM_001172, NP_001163
- UniProt
- P78540
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