LAMa4 Antikörper (C-Term)

Produktnummer ABIN2785769

Produktdetails anti-LAMa4 Antikörper

Target: LAMa4 (Laminin, alpha 4 (LAMa4))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LAMa4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: HCHPAGAPAP PRAVPHSSFS LSPPLSSPQC LESFTWARSV RKLEIKSFPL

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against LAMA4. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 120 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu LAMa4

Target: LAMa4 (Laminin, alpha 4 (LAMa4))

Andere Bezeichnung: LAMA4 (LAMa4 Produkte)

Synonyme: si:dkey-119m7.3 antikoerper, si:busm1-189a20.2 antikoerper, CMD1JJ antikoerper, LAMA3 antikoerper, LAMA4*-1 antikoerper, RGD1560062 antikoerper, laminin subunit alpha 4 antikoerper, laminin, alpha 4 antikoerper, LAMA4 antikoerper, lama4 antikoerper, Lama4 antikoerper

Hintergrund: Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms. This gene encodes the alpha chain isoform laminin, alpha 4. The domain structure of alpha 4 is similar to that of alpha 3, both of which resemble truncated versions of alpha 1 and alpha 2, in that approximately 1,200 residues at the N-terminus (domains IV, V and VI) have been lost. Laminin, alpha 4 contains the C-terminal G domain which distinguishes all alpha chains from the beta and gamma chains. The RNA analysis from adult and fetal tissues revealed developmental regulation of expression, however, the exact function of laminin, alpha 4 is not known. Tissue-specific utilization of alternative polyA-signal has been described in literature.
Alias Symbols: DKFZp686D23145, LAMA3, LAMA4*-1
Protein Interaction Partner: RTN4, APC, LRIF1, COPS6, MED31, BRD7, ZHX1, ATF7IP, UBR1, UNC119, TP53, PTN, GAPDH, EEF1A1, TUBB2A,
Protein Size: 120

Molekulargewicht: 10 kDa

Gen-ID: 3910

NCBI Accession: NM_001105209, NP_001098679

Pathways: Brown Fat Cell Differentiation