ACVR1C/ALK7 Antikörper (N-Term)
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- Target Alle ACVR1C/ALK7 (ACVR1C) Antikörper anzeigen
- ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Schwein, Hund, Kaninchen, Meerschweinchen, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ACVR1C/ALK7 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- QVFCHSSNNV TKTECCFTDF CNNITLHLPT ASPNAPKLGP MELAIIITVP
- Homologie
- Cow: 100%, Dog: 83%, Guinea Pig: 80%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 81%, Rabbit: 100%, Rat: 86%
- Produktmerkmale
- This is a rabbit polyclonal antibody against ACVR1C. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human ACVR1C
- Top Product
- Discover our top product ACVR1C Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 493 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
- Andere Bezeichnung
- ACVR1C (ACVR1C Produkte)
- Synonyme
- ACVRLK7 antikoerper, ALK7 antikoerper, Alk-7 antikoerper, C230097P10 antikoerper, Alk7 antikoerper, habrec1 antikoerper, activin A receptor type 1C antikoerper, activin A receptor, type IC antikoerper, ACVR1C antikoerper, Acvr1c antikoerper
- Hintergrund
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ACVR1C is a type I receptor for the TGFB family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors.ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM].
Alias Symbols: ACVRLK7, ALK7
Protein Interaction Partner: HSP90AA1, TDGF1, INHBB,
Protein Size: 493 - Molekulargewicht
- 55 kDa
- Gen-ID
- 130399
- NCBI Accession
- NM_145259, NP_660302
- UniProt
- Q8NER5
- Pathways
- Negative Regulation of Hormone Secretion, Positive Regulation of Endopeptidase Activity
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