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ACVR1C/ALK7 Antikörper (N-Term)

ACVR1C Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Hund, Kaninchen, Meerschweinchen, Pferd WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2785115
  • Target Alle ACVR1C/ALK7 (ACVR1C) Antikörper anzeigen
    ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
    Bindungsspezifität
    • 16
    • 9
    • 8
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 44
    • 42
    • 28
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Schwein, Hund, Kaninchen, Meerschweinchen, Pferd
    Wirt
    • 53
    • 5
    Kaninchen
    Klonalität
    • 55
    • 3
    Polyklonal
    Konjugat
    • 28
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ACVR1C/ALK7 Antikörper ist unkonjugiert
    Applikation
    • 50
    • 25
    • 20
    • 13
    • 13
    • 11
    • 9
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    QVFCHSSNNV TKTECCFTDF CNNITLHLPT ASPNAPKLGP MELAIIITVP
    Homologie
    Cow: 100%, Dog: 83%, Guinea Pig: 80%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 81%, Rabbit: 100%, Rat: 86%
    Produktmerkmale
    This is a rabbit polyclonal antibody against ACVR1C. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human ACVR1C
    Top Product
    Discover our top product ACVR1C Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 493 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
    Andere Bezeichnung
    ACVR1C (ACVR1C Produkte)
    Synonyme
    ACVRLK7 antikoerper, ALK7 antikoerper, Alk-7 antikoerper, C230097P10 antikoerper, Alk7 antikoerper, habrec1 antikoerper, activin A receptor type 1C antikoerper, activin A receptor, type IC antikoerper, ACVR1C antikoerper, Acvr1c antikoerper
    Hintergrund
    ACVR1C is a type I receptor for the TGFB family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors.ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM].
    Alias Symbols: ACVRLK7, ALK7
    Protein Interaction Partner: HSP90AA1, TDGF1, INHBB,
    Protein Size: 493
    Molekulargewicht
    55 kDa
    Gen-ID
    130399
    NCBI Accession
    NM_145259, NP_660302
    UniProt
    Q8NER5
    Pathways
    Negative Regulation of Hormone Secretion, Positive Regulation of Endopeptidase Activity
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