NTRK3 Antikörper (C-Term)

Produktnummer ABIN2784511

Produktdetails anti-NTRK3 Antikörper

Target: NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Schwein, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NTRK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ERPRVCPKEV YDVMLGCWQR EPQQRLNIKE IYKILHALGK ATPIYLDILG

Homologie: Cow: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against NTRK3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NTRK3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 825 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NTRK3

Target: NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))

Andere Bezeichnung: NTRK3 (NTRK3 Produkte)

Synonyme: TRKC antikoerper, gp145(trkC) antikoerper, trkC antikoerper, AW125844 antikoerper, Ntrk3_tv3 antikoerper, TrkC antikoerper, neurotrophic receptor tyrosine kinase 3 antikoerper, neurotrophic tyrosine kinase, receptor, type 3 antikoerper, NTRK3 antikoerper, Ntrk3 antikoerper

Hintergrund: NTRK3 is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.
Alias Symbols: TRKC, gp145(trkC)
Protein Interaction Partner: TNK2, IRAK3, HSP90AA1, APP, SHC2, KIDINS220, DOK5, RASGRF1, MAPK3, DYNLL1, SQSTM1, SHC1, NGFRAP1, IRAK1, HTR2A, MAPK1, PTPN1, PLCG1, JUN, NTF3, NGFR, FRS2,
Protein Size: 825

Molekulargewicht: 89 kDa

Gen-ID: 4916

NCBI Accession: NM_002530, NP_002521

Pathways: RTK Signalweg, Neurotrophin Signalübertragung, Regulation of Cell Size