TRKB Antikörper (C-Term)

Produktnummer ABIN2784510

Produktdetails anti-TRKB Antikörper

Target: TRKB (NTRK2) (Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Kaninchen, Rind (Kuh), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRKB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: DFSWFGFGKV KSRQGVGPAS VISNDDDSAS PLHHISNGSN TPSSSEGGPD

Homologie: Cow: 88%, Horse: 100%, Human: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against NTRK2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NTRK2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 553 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TRKB

Target: TRKB (NTRK2) (Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))

Andere Bezeichnung: NTRK2 (NTRK2 Produkte)

Synonyme: trkb antikoerper, trkb-b antikoerper, xtrkb antikoerper, si:ch211-220b11.1 antikoerper, trkB2 antikoerper, NTRK2 antikoerper, ntrk2 antikoerper, gp145-trkb antikoerper, TRKB antikoerper, GP145-TrkB antikoerper, trk-B antikoerper, AI848316 antikoerper, C030027L06Rik antikoerper, Tkrb antikoerper, trkB antikoerper, RATTRKB1 antikoerper, TRKB1 antikoerper, Trk-B antikoerper, TrkB antikoerper, neurotrophic receptor tyrosine kinase 2 antikoerper, neurotrophic receptor tyrosine kinase 2 L homeolog antikoerper, neurotrophic tyrosine kinase, receptor, type 2b antikoerper, neurotrophic receptor tyrosine kinase 2 S homeolog antikoerper, neurotrophic tyrosine kinase, receptor, type 2 antikoerper, NTRK2 antikoerper, ntrk2.L antikoerper, ntrk2b antikoerper, ntrk2.S antikoerper, ntrk2 antikoerper, Ntrk2 antikoerper

Hintergrund: This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders.
Alias Symbols: GP145-TrkB, TRKB, trk-B
Protein Interaction Partner: TNK2, RANBP9, POLR2G, HSP90AA1, AP1B1, NMNAT1, UBC, NTF4, Nedd4, SHC2, KIDINS220, DOK5, SH2B2, SH2B1, SHC3, RASGRF1, UBB, FRS3, GIPC1, NCK2, DYNLL1, SQSTM1, SHC1, NCK1, NTRK2, PTPN1, PTPN11, PLCG1, NTF3, NGFR, FYN, BDNF, TRAF6, PIK3R1, FRS2,
Protein Size: 553

Molekulargewicht: 57 kDa

Gen-ID: 4915

NCBI Accession: NM_001018065, NP_001018075

UniProt: Q8WXJ5

Pathways: RTK Signalweg, Neurotrophin Signalübertragung, cAMP Metabolic Process, Skeletal Muscle Fiber Development, Feeding Behaviour, Dicarboxylic Acid Transport