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PTP4A3 Antikörper (Middle Region)

PTP4A3 Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2784453
  • Target Alle PTP4A3 Antikörper anzeigen
    PTP4A3 (Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))
    Bindungsspezifität
    • 12
    • 8
    • 6
    • 3
    • 2
    • 1
    • 1
    Middle Region
    Reaktivität
    • 50
    • 23
    • 11
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio)
    Wirt
    • 47
    • 3
    Kaninchen
    Klonalität
    • 48
    • 2
    Polyklonal
    Konjugat
    • 23
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PTP4A3 Antikörper ist unkonjugiert
    Applikation
    • 36
    • 22
    • 10
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    LGRAPVLVAL ALIESGMKYE DAIQFIRQKR RGAINSKQLT YLEKYRPKQR
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against PTP4A3. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human PTP4A3
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 173 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    PTP4A3 (Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))
    Andere Bezeichnung
    PTP4A3 (PTP4A3 Produkte)
    Synonyme
    PRL-3 antikoerper, PRL-R antikoerper, PRL3 antikoerper, wu:fc54b05 antikoerper, wu:fv52d11 antikoerper, zgc:77109 antikoerper, prl-3 antikoerper, prl3 antikoerper, ptpcaax3 antikoerper, PTP4A3 antikoerper, AV088979 antikoerper, Prl-3 antikoerper, pPtp4a3 antikoerper, protein tyrosine phosphatase type IVA, member 3 antikoerper, protein tyrosine phosphatase type IVA, member 3 L homeolog antikoerper, protein tyrosine phosphatase 4a3 antikoerper, PTP4A3 antikoerper, ptp4a3 antikoerper, ptp4a3.L antikoerper, Ptp4a3 antikoerper
    Hintergrund
    PTP4A3 belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contains a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth.The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist.
    Alias Symbols: PRL-3, PRL-R, PRL3
    Protein Interaction Partner: ELAVL1, FNTB, FNTA, IPO4, MMS19, NCAPG, SMAP1, SRPRB, XPO5, TTC27, FANCI, ATAD3A, TMEM33, HEATR1, DNAAF5, TNPO2, CNNM3, KIAA1279, RAB3GAP2, NUP188, KIAA0368, XPO7, GCN1L1, SMC2, LRPPRC, UBE4A, AIFM1, USO1, ABCD3, PSMD3, PRPSAP1, POLD1, HNRNPM, MSH2, MCM3,
    Protein Size: 173
    Molekulargewicht
    19 kDa
    Gen-ID
    11156
    NCBI Accession
    NM_032611, NP_116000
    UniProt
    O75365
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