COL25A1 Antikörper (Middle Region)

Produktnummer ABIN2784040

Produktdetails anti-COL25A1 Antikörper

Target: COL25A1 (Collagen, Type XXV, alpha 1 (COL25A1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Schwein, Kaninchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COL25A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GERGEAGPPG RGERGEPGAP GPKGKQGESG TRGPKGSKGD RGEKGDSGAQ

Homologie: Cow: 85%, Dog: 100%, Guinea Pig: 80%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 85%, Rabbit: 86%, Rat: 93%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against COL25A1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human COL25A1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 642 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu COL25A1

Target: COL25A1 (Collagen, Type XXV, alpha 1 (COL25A1))

Andere Bezeichnung: COL25A1 (COL25A1 Produkte)

Synonyme: COL25A1 antikoerper, AMY antikoerper, CLAC antikoerper, CLAC-P antikoerper, CLACP antikoerper, 2700062B08Rik antikoerper, collagen type XXV alpha 1 chain antikoerper, collagen, type XXV, alpha 1 antikoerper, COL25A1 antikoerper, col25a1 antikoerper, Col25a1 antikoerper

Hintergrund: COL25A1 is a brain-specific membrane-bound collagen. Proteolytic processing releases CLAC, a soluble form of COL25A1 containing the extracellular collagen domains that associates with senile plaques in Alzheimer disease (AD) brains. COL25A1 is a brain-specific membrane-bound collagen. Proteolytic processing releases CLAC, a soluble form of COL25A1 containing the extracellular collagen domains that associates with senile plaques in Alzheimer disease (AD, MIM 104300) brains (Osada et al., 2005 [PubMed 15615705]).[supplied by OMIM].
Alias Symbols: CLAC, AMY, CLACP, CLAC-P
Protein Interaction Partner: COL25A1, APP, SNCA, IAPP,
Protein Size: 642

Molekulargewicht: 64 kDa

Gen-ID: 84570

NCBI Accession: NM_032518, NP_115907

UniProt: Q9BXS0