WNT3 Antikörper (Middle Region)

Produktnummer ABIN2783983

Produktdetails anti-WNT3 Antikörper

Target: WNT3 (Wingless-Type MMTV Integration Site Family, Member 3 (WNT3))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Zebrafisch (Danio rerio), Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WNT3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SHHKGPPGEG WKWGGCSEDA DFGVLVSREF ADARENRPDA RSAMNKHNNE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against WNT3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human WNT3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 355 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu WNT3

Target: WNT3 (Wingless-Type MMTV Integration Site Family, Member 3 (WNT3))

Andere Bezeichnung: WNT3 (WNT3 Produkte)

Synonyme: INT4 antikoerper, Ci-Wnt3 antikoerper, WNT3 antikoerper, int4 antikoerper, Xwnt3 antikoerper, wnt-3 antikoerper, wnt3l antikoerper, Xwnt-3 antikoerper, wnt3 antikoerper, Int-4 antikoerper, Wnt-3 antikoerper, wnt3-A antikoerper, Wnt family member 3 antikoerper, wingless-type MMTV integration site family, member 3 antikoerper, proto-oncogene Wnt-3 antikoerper, wingless-type MMTV integration site family member 3 antikoerper, Wnt family member 3A antikoerper, wingless-type MMTV integration site family member 3 L homeolog antikoerper, WNT3 antikoerper, Wnt3 antikoerper, wnt3 antikoerper, LOC468297 antikoerper, WNT3A antikoerper, wnt3.L antikoerper

Hintergrund: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98 % amino acid identity to mouse Wnt3 protein, and 84 % to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.
Alias Symbols: INT4, MGC131950, MGC138321, MGC138323
Protein Interaction Partner: FZD1,
Protein Size: 355

Molekulargewicht: 37 kDa

Gen-ID: 7473

NCBI Accession: NM_030753, NP_110380

UniProt: P56703

Pathways: WNT Signalweg, Regulation of Cell Size