PAK4 Antikörper (Middle Region)
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- Target Alle PAK4 Antikörper anzeigen
- PAK4 (P21-Activated Kinase 4 (PAK4))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PAK4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- EPQLAPPACT PAAPAVPGPP GPRSPQREPQ RVSHEQFRAA LQLVVDPGDP
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against PAK4. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human PAK4
- Top Product
- Discover our top product PAK4 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeat freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PAK4 (P21-Activated Kinase 4 (PAK4))
- Andere Bezeichnung
- PAK4 (PAK4 Produkte)
- Synonyme
- 5730488L07Rik antikoerper, AW555722 antikoerper, mKIAA1142 antikoerper, im:5916170 antikoerper, wu:fd12b01 antikoerper, zgc:92014 antikoerper, p21 (RAC1) activated kinase 4 antikoerper, p21 protein (Cdc42/Rac)-activated kinase 4 antikoerper, PAK4 antikoerper, Pak4 antikoerper, pak4 antikoerper
- Hintergrund
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PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: -
Protein Interaction Partner: SH3RF2, HECW2, UBC, LATS2, YWHAQ, YWHAB, SRPK2, SRPK1, FBXO25, YWHAE, APP, POT1, TERF1, YWHAZ, YWHAG, RAN, CDC42, GATAD2A, PAK4, LIMK1, ITGAV, FGFR2, ITGB5, DLST, GRB2, RAC1, LRRK1, SFN, SSH1,
Protein Size: 591 - Molekulargewicht
- 65 kDa
- Gen-ID
- 10298
- NCBI Accession
- NM_005884, NP_005875
- UniProt
- O96013
- Pathways
- RTK Signalweg
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