PSMD8 Antikörper (C-Term)

Produktnummer ABIN2783285

Produktdetails anti-PSMD8 Antikörper

Target: PSMD8 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMD8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: DYAKKRGWVL GPNNYYSFAS QQQKPEDTTI PSTELAKQVI EYARQLEMIV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PSMD8. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PSMD8

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 257 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PSMD8

Target: PSMD8 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8))

Andere Bezeichnung: PSMD8 (PSMD8 Produkte)

Synonyme: HIP6 antikoerper, HYPF antikoerper, Nin1p antikoerper, Rpn12 antikoerper, S14 antikoerper, p31 antikoerper, hip6 antikoerper, hypf antikoerper, nin1p antikoerper, rpn12 antikoerper, psmd8b antikoerper, 6720456J22Rik antikoerper, AA407360 antikoerper, AL033291 antikoerper, AL033322 antikoerper, AL033323 antikoerper, C76433 antikoerper, psmd8 antikoerper, psmd8a antikoerper, fa93g07 antikoerper, fb17c09 antikoerper, fb49a10 antikoerper, zgc:86762 antikoerper, wu:fa93g07 antikoerper, wu:fb17c09 antikoerper, wu:fb49a10 antikoerper, PSMD8 antikoerper, proteasome 26S subunit, non-ATPase 8 antikoerper, proteasome 26S subunit, non-ATPase 8 S homeolog antikoerper, proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 antikoerper, proteasome 26S subunit, non-ATPase 8 L homeolog antikoerper, proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 pseudogene antikoerper, PSMD8 antikoerper, psmd8.S antikoerper, Psmd8 antikoerper, psmd8.L antikoerper, psmd8 antikoerper, LOC468490 antikoerper

Hintergrund: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. PSMD8 is a non-ATPase subunit of the 19S regulator. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.
Alias Symbols: HIP6, HYPF, MGC1660, Nin1p, Rpn12, S14, p31
Protein Interaction Partner: HUWE1, UBC, PSMD14, TXNL1, PPFIA1, RPS21, RPS12, RPS8, PSMD11, PSMD7, PSMD4, PSMD3, PSMD2, PSMD1, PSMC6, PSMC5, PSMC4, PSMC2, PSMC1, MAP2, DYNC1I2, DHX9, ABCF1, KCMF1, UCHL5, DYNC1LI1, KIAA0368, ADRM1, HNRNPA0, PARK2, RNF11, BAG3, NOS2, SMAD9, SMAD2, PSMD
Protein Size: 257

Molekulargewicht: 27 kDa

Gen-ID: 5714

UniProt: P48556

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Proton Transport, Synthesis of DNA, SARS-CoV-2 Protein Interaktom, Ubiquitin Proteasome Pathway