WNT6 Antikörper (Middle Region)

Produktnummer ABIN2782719

Produktdetails anti-WNT6 Antikörper

Target: WNT6 (Wingless-Type MMTV Integration Site Family, Member 6 (WNT6))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Rind (Kuh), Hund, Kaninchen, Ratte, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WNT6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ERFHGASRVM GTNDGKALLP AVRTLKPPGR ADLLYAADSP DFCAPNRRTG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against WNT6. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human WNT6

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 365 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu WNT6

Target: WNT6 (Wingless-Type MMTV Integration Site Family, Member 6 (WNT6))

Andere Bezeichnung: WNT6 (WNT6 Produkte)

Synonyme: WNT6 antikoerper, si:dkey-31m21.2 antikoerper, Wnt6 antikoerper, AA409270 antikoerper, Wnt-6 antikoerper, Xwnt-6 antikoerper, wnt-6 antikoerper, wnt6-A antikoerper, xWnt6 antikoerper, Wnt family member 6 antikoerper, wingless-type MMTV integration site family, member 6b antikoerper, wingless-type MMTV integration site family, member 6 antikoerper, Wnt family member 6 S homeolog antikoerper, WNT6 antikoerper, Wnt6 antikoerper, wnt6b antikoerper, wnt6.S antikoerper

Hintergrund: The WNT family consists of several secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT6 is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The WNT6 protein overexpression may play key roles in carcinogenesis. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97 % identical to the mouse Wnt6 protein at the amino acid level.
Alias Symbols: -
Protein Interaction Partner: PORCN,
Protein Size: 365

Molekulargewicht: 37 kDa

Gen-ID: 7475

NCBI Accession: NM_006522, NP_006513

UniProt: Q9Y6F9

Pathways: WNT Signalweg, Tube Formation