RFC3 Antikörper (N-Term)

Produktnummer ABIN2782475

Produktdetails anti-RFC3 Antikörper

Target: RFC3 (Replication Factor C (Activator 1) 3, 38kDa (RFC3))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RFC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: YHLEVNPSDA GNSDRVVIQE MLKTVAQSQQ LETNSQRDFK VVLLTEVDKL

Homologie: Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RFC3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RFC3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 356 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RFC3

Target: RFC3 (Replication Factor C (Activator 1) 3, 38kDa (RFC3))

Andere Bezeichnung: RFC3 (RFC3 Produkte)

Synonyme: CG5313 antikoerper, DRFC antikoerper, DmRFC3 antikoerper, Dmel\\CG5313 antikoerper, Rfc3 antikoerper, 21.m02902 antikoerper, 2810416I22Rik antikoerper, 38kDa antikoerper, AU022547 antikoerper, Recc3 antikoerper, cb275 antikoerper, RFC38 antikoerper, Replication factor C subunit 3 antikoerper, replication factor C3 antikoerper, replication factor C subunit 3 antikoerper, replication factor C 38 kDa subunit antikoerper, DNA replication factor C complex subunit Rfc3 antikoerper, replication factor C3, putative antikoerper, replication factor C (activator 1) 3 antikoerper, replication factor C subunit 3 L homeolog antikoerper, RfC3 antikoerper, PF14_0601 antikoerper, Chro.30359 antikoerper, PB000006.01.0 antikoerper, PC000345.04.0 antikoerper, TP04_0380 antikoerper, Tb09.211.3310 antikoerper, PY04255 antikoerper, PVX_117300 antikoerper, BBOV_IV003080 antikoerper, SJAG_02182 antikoerper, PKH_124240 antikoerper, rfc3 antikoerper, Rfc3 antikoerper, RFC3 antikoerper, rfc3.L antikoerper

Hintergrund: The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. RFC3 is the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits.The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 38 kD subunit. This subunit is essential for the interaction between the 140 kD subunit and the core complex that consists of the 36, 37, and 40 kD subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Alias Symbols: MGC5276, RFC38
Protein Interaction Partner: PCNA, TP53, UBC, RPA3, RPA2, RPA1, RPP40, FBXO6, ARFGAP1, VCP, RFC4, RFC5, RFC2, RFC1, PURB, PURA, MCM3, Cebpb, RAD21, HDGF, SMARCAD1, EBNA-LP, MESDC2, MYC, FAN1, MEPCE, USP20, CHTF8, RAD17, BRD4, CHTF18,
Protein Size: 356

Molekulargewicht: 40 kDa

Gen-ID: 5983

NCBI Accession: NM_002915, NP_002906

UniProt: P40938

Pathways: Telomere Maintenance, DNA Reparatur, DNA Replication, Synthesis of DNA