DEGS1 Antikörper (N-Term)

Produktnummer ABIN2782243

Produktdetails anti-DEGS1 Antikörper

Target: DEGS1 (Sphingolipid Delta(4)-Desaturase DES1 (DEGS1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd, Kaninchen, Schaf, Zebrafisch (Danio rerio), Rind (Kuh), Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DEGS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: GSRVSREDFE WVYTDQPHAD RRREILAKYP EIKSLMKPDP NLIWIIIMMV

Homologie: Cow: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 93%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against DEGS1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DEGS1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 323 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DEGS1

Target: DEGS1 (Sphingolipid Delta(4)-Desaturase DES1 (DEGS1))

Andere Bezeichnung: DEGS1 (DEGS1 Produkte)

Synonyme: DEGS antikoerper, DEGS-1 antikoerper, DES1 antikoerper, Des-1 antikoerper, FADS7 antikoerper, MLD antikoerper, degs antikoerper, im:6909319 antikoerper, wu:fa25h01 antikoerper, wu:fb81d06 antikoerper, Degs antikoerper, AA536663 antikoerper, Des1 antikoerper, Mdes antikoerper, delta 4-desaturase, sphingolipid 1 antikoerper, delta(4)-desaturase, sphingolipid 1 antikoerper, DEGS1 antikoerper, degs1 antikoerper, Degs1 antikoerper

Hintergrund: DEGS1 is a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this protein inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor.This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. Two splice variants have been identified.
Alias Symbols: DEGS, DES1, Des-1, FADS7, MGC5079, MIG15, MLD, DEGS-1
Protein Interaction Partner: UBC, NAGPA, UBD, EGFR, TSSC1, SURF4, SLC16A1, PYGM,
Protein Size: 323

Molekulargewicht: 38 kDa

Gen-ID: 8560

NCBI Accession: NM_003676, NP_003667

UniProt: O15121