PTPRA Antikörper (C-Term)

Produktnummer ABIN2782196

Produktdetails anti-PTPRA Antikörper

Target: PTPRA (Protein tyrosine Phosphatase, Receptor Type, A (PTPRA))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Zebrafisch (Danio rerio), Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTPRA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SRQIRQFHFH GWPEVGIPSD GKGMISIIAA VQKQQQQSGN HPITVHCSAG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PTPRA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PTPRA

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 802 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PTPRA

Target: PTPRA (Protein tyrosine Phosphatase, Receptor Type, A (PTPRA))

Andere Bezeichnung: PTPRA (PTPRA Produkte)

Synonyme: PTPRA antikoerper, heptp antikoerper, hlpr antikoerper, hptpa antikoerper, hptpalpha antikoerper, lrp antikoerper, ptpa antikoerper, ptprl2 antikoerper, r-ptp-alpha antikoerper, rptpa antikoerper, HEPTP antikoerper, HLPR antikoerper, HPTPA antikoerper, HPTPalpha antikoerper, LRP antikoerper, PTPA antikoerper, PTPRL2 antikoerper, R-PTP-alpha antikoerper, RPTPA antikoerper, Ptpa antikoerper, Ptpalpha antikoerper, Rptpalpha antikoerper, Rptra antikoerper, Rptralpha antikoerper, RPTP[a] antikoerper, zf-RPTP[a] antikoerper, ptpa-a antikoerper, protein tyrosine phosphatase, receptor type A antikoerper, protein tyrosine phosphatase, receptor type, A antikoerper, protein tyrosine phosphatase, receptor type A S homeolog antikoerper, PTPRA antikoerper, ptpra antikoerper, Ptpra antikoerper, ptpra.S antikoerper

Hintergrund: PTPRA is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPRA contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. PTPRA has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported.
Alias Symbols: HEPTP, HLPR, HPTPA, HPTPalpha, LRP, PTPA, PTPRL2, R-PTP-alpha, RPTPA
Protein Interaction Partner: UBC, GRB2, CALM1, GABARAPL2, UVRAG, BCAR1, PTPRD, PTPRS, SRC, PTPRF, PRKCD, PTPRM, PTPRA, KCNA2, FYN,
Protein Size: 802

Molekulargewicht: 89 kDa

Gen-ID: 5786

NCBI Accession: NM_002836, NP_002827

UniProt: P18433