Osteoactivin (N-Term) Antikörper

Details zu Produkt Nr. ABIN2781893, Anbieter: Anmelden zum Anzeigen
Antigen
  • HGFIN
  • NMB
  • DC-HIL
  • Dchil
  • ipd
  • glycoprotein nmb
  • glycoprotein (transmembrane) nmb
  • glycoprotein nmb L homeolog
  • Gpnmb
  • GPNMB
  • gpnmb.L
Epitop
N-Term
20
18
15
11
9
8
8
6
5
4
4
3
2
2
2
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus)
120
27
23
4
4
4
3
3
2
2
2
1
1
Wirt
Kaninchen
66
59
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
5
5
4
4
4
3
3
3
3
3
3
3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
77
60
37
20
15
13
4
3
3
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human GPNMB
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN977597.
Sequenz DENDWNEKLY PVWKRGDMRW KNSWKGGRVQ AVLTSDSPAL VGSNITFAVN
Spezifität 100 % homologous to both isoforms of hGPNMB
Homologie Cow: 100%, Dog: 79%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%
Produktmerkmale This is a rabbit polyclonal antibody against GPNMB. It was validated on Western Blot and immunohistochemistry.
Reinigung Affinity Purified
Andere Bezeichnung GPNMB
Hintergrund GPNMB is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential.The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: HGFIN, NMB
Protein Interaction Partner: UBC, SMAD4, ITSN2,
Protein Size: 560
Molekulargewicht 63 kDa
Gen-ID 10457
NCBI Accession NM_002510, NP_002501
UniProt Q14956
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 560 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Osteoactivin (N-Term) antibody (ABIN2781893) anti-Osteoactivin (N-Term) antibody
Allgemeine Veröffentlichungen Oh, Yang, Hahn, Kim, Byun, Jeon, Kim, Song, Noh, Kim, Yoo, Kim, Kim: "Transcriptome analysis of human gastric cancer." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 16, Issue 12, pp. 942-54, 2005 (PubMed).

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