C1QB Antikörper (Middle Region)
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- Target Alle C1QB Antikörper anzeigen
- C1QB (Complement Component 1, Q Subcomponent, B Chain (C1QB))
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Bindungsspezifität
- Middle Region
- Reaktivität
- Human, Maus, Ratte, Hund, Pferd, Schwein, Kaninchen, Rind (Kuh), Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser C1QB Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- PGPKGESGDY KATQKIAFSA TRTINVPLRR DQTIRFDHVI TNMNNNYEPR
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 100%, Rabbit: 100%, Rat: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against C1QB. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human C1QB
- Top Product
- Discover our top product C1QB Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 253 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- C1QB (Complement Component 1, Q Subcomponent, B Chain (C1QB))
- Andere Bezeichnung
- C1QB (C1QB Produkte)
- Synonyme
- complement C1q B chain antikoerper, complement component 1, q subcomponent, beta polypeptide antikoerper, C1QB antikoerper, C1qb antikoerper
- Hintergrund
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C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca2+-dependent C1r2C1s2 proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the B-chain polypeptide of human complement subcomponent C1q. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: IL32, EED, FN1, EDA2R, RELA, MYOC, PTX3, C1R, HRG, DEFA1, C1QC, C1QA,
Protein Size: 253 - Molekulargewicht
- 27 kDa
- Gen-ID
- 713
- NCBI Accession
- NM_000491, NP_000482
- UniProt
- P02746
- Pathways
- Komplementsystem
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