SLC5A8 Antikörper (Middle Region)
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- Target Alle SLC5A8 Antikörper anzeigen
- SLC5A8 (Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SLC5A8 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- GILVPFANSI GALVGLMAGF AISLWVGIGA QIYPPLPERT LPLHLDIQGC
- Homologie
- Human: 100%, Mouse: 83%, Rabbit: 92%, Rat: 91%
- Produktmerkmale
- This is a rabbit polyclonal antibody against SLC5A8. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human SLC5A8
- Top Product
- Discover our top product SLC5A8 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 610 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Molecular mechanism of SLC5A8 inactivation in breast cancer." in: Molecular and cellular biology, Vol. 33, Issue 19, pp. 3920-35, (2013) (PubMed).
: "Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate." in: Oncogene, Vol. 30, Issue 38, pp. 4026-37, (2011) (PubMed).
: "Activin A induces SLC5A8 expression through the Smad3 signaling pathway in human colon cancer RKO cells." in: The international journal of biochemistry & cell biology, Vol. 42, Issue 12, pp. 1964-72, (2010) (PubMed).
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Molecular mechanism of SLC5A8 inactivation in breast cancer." in: Molecular and cellular biology, Vol. 33, Issue 19, pp. 3920-35, (2013) (PubMed).
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- Target
- SLC5A8 (Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8))
- Andere Bezeichnung
- SLC5A8 (SLC5A8 Produkte)
- Synonyme
- Ait antikoerper, SMCT antikoerper, SMCT1 antikoerper, AIT antikoerper, RGD1564146 antikoerper, solute carrier family 5 (iodide transporter), member 8 antikoerper, solute carrier family 5 member 8 antikoerper, Slc5a8 antikoerper, SLC5A8 antikoerper
- Hintergrund
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SLC5A8 has been shown to transport iodide by a passive mechanism (Rodriguez et al., 2002 [PubMed 12107270]) and monocarboxylates and short-chain fatty acids by a sodium-coupled mechanism (Gopal et al., 2004 [PubMed 15322102]). In kidney, SLC5A8 functions
Alias Symbols: AIT, MGC125354, SMCT, SMCT1
Protein Size: 610 - Molekulargewicht
- 66 kDa
- Gen-ID
- 160728
- NCBI Accession
- NM_145913, NP_666018
- UniProt
- Q8N695
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