SLCO1B1 Antikörper (Middle Region)

Produktnummer ABIN2781625

Produktdetails anti-SLCO1B1 Antikörper

Target: SLCO1B1 (Solute Carrier Organic Anion Transporter Family, Member 1B1 (SLCO1B1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Rind (Kuh), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLCO1B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: IILIYAMKKK YQEKDINASE NGSVMDEANL ESLNKNKHFV PSAGADSETH

Homologie: Cow: 86%, Human: 100%, Pig: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against SLCO1B1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SLCO1B1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 691 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SLCO1B1

Target: SLCO1B1 (Solute Carrier Organic Anion Transporter Family, Member 1B1 (SLCO1B1))

Andere Bezeichnung: SLCO1B1 (SLCO1B1 Produkte)

Synonyme: HBLRR antikoerper, LST-1 antikoerper, LST1 antikoerper, OATP-C antikoerper, OATP1B1 antikoerper, OATP2 antikoerper, OATPC antikoerper, SLC21A6 antikoerper, SLCO1B1 antikoerper, solute carrier organic anion transporter family member 1B1 antikoerper, SLCO1B1 antikoerper, LOC100011628 antikoerper, LOC100448597 antikoerper

Hintergrund: This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function.
Alias Symbols: LST-1, MGC133282, OATP-C, OATP1B1, OATP2, SLC21A6, LST1, HBLRR, OATPC
Protein Size: 691

Molekulargewicht: 76 kDa

Gen-ID: 10599

NCBI Accession: NM_006446, NP_006437

UniProt: Q9Y6L6