SLC25A20 Antikörper (C-Term)

Produktnummer ABIN2781540

Produktdetails anti-SLC25A20 Antikörper

Target: SLC25A20 (Solute Carrier Family 25 (Carnitine/acylcarnitine Translocase), Member 20 (SLC25A20))

Bindungsspezifität: C-Term

Reaktivität: Maus, Human, Ratte, Rind (Kuh), Schaf, Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC25A20 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GGIAGIFNWA VAIPPDVLKS RFQTAPPGKY PNGFRDVLRE LIRDEGVTSL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against SLC25A20. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SLC25A20

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 301 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SLC25A20 Antikörper (ABIN2781540)

Pierre, Macdonald, Gray, Hendriksz, Preece, Chakrapani: "Prospective treatment in carnitine-acylcarnitine translocase deficiency." in: Journal of inherited metabolic disease, Vol. 30, Issue 5, pp. 815, (2007) (PubMed).

Details zu SLC25A20

Target: SLC25A20 (Solute Carrier Family 25 (Carnitine/acylcarnitine Translocase), Member 20 (SLC25A20))

Andere Bezeichnung: SLC25A20 (SLC25A20 Produkte)

Synonyme: 5848 antikoerper, BG:DS02740.15 antikoerper, CACT antikoerper, CG5848 antikoerper, Cact antikoerper, Dmel\\CG5848 antikoerper, cac antikoerper, dip6 antikoerper, fs(2)ltoRN48 antikoerper, n(2)k17003 antikoerper, cact antikoerper, dif-1 antikoerper, SLC25A20 antikoerper, DKFZp468F1219 antikoerper, zgc:77760 antikoerper, PRKAR2A antikoerper, CAC antikoerper, 1110007P09Rik antikoerper, C78826 antikoerper, mCAC antikoerper, cactus antikoerper, solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 antikoerper, solute carrier family 25 member 20 antikoerper, solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 L homeolog antikoerper, solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20 antikoerper, cact antikoerper, slc25a20 antikoerper, SLC25A20 antikoerper, Slc25a20 antikoerper, slc25a20.L antikoerper

Hintergrund: SLC25A20 is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space.It mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants.This gene product is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CAC, CACT
Protein Interaction Partner: KDM1A, ESR1, UBC, HN1L,
Protein Size: 301

Molekulargewicht: 33 kDa

Gen-ID: 788

NCBI Accession: NM_000387, NP_000378

UniProt: P97521

Pathways: T-Zell Rezeptor Signalweg, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades