ABCB8 Antikörper (Middle Region)
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- Target Alle ABCB8 Antikörper anzeigen
- ABCB8 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 8 (ABCB8))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ABCB8 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- EPVLFGTTIM ENIRFGKLEA SDEEVYTAAR EANAHEFITS FPEGYNTVVG
- Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against ABCB8. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human ABCB8
- Top Product
- Discover our top product ABCB8 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 718 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ABCB8 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 8 (ABCB8))
- Andere Bezeichnung
- ABCB8 (ABCB8 Produkte)
- Synonyme
- EST328128 antikoerper, M-ABC1 antikoerper, MABC1 antikoerper, 4833412N02Rik antikoerper, AA409895 antikoerper, ABCB8 antikoerper, zgc:113037 antikoerper, ATP binding cassette subfamily B member 8 antikoerper, ATP-binding cassette, sub-family B (MDR/TAP), member 8 antikoerper, ABCB8 antikoerper, Abcb8 antikoerper, abcb8 antikoerper
- Hintergrund
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The membrane-associated protein ABCB8 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC proteins are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). ABCB8 is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined, however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. This protein may also play a role in the transport of phospholipids into mitochondrial membranes.The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined, however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. This protein may also play a role in the transport of phospholipids into mitochondrial membranes.
Alias Symbols: EST328128, M-ABC1, MABC1
Protein Interaction Partner: UBC, FMNL1, LDHAL6B, ADPGK, IMPAD1, MTERF3, RAB11FIP5, PROCR, RASGRP1, NOA1, ABCB8, SAT1,
Protein Size: 718 - Molekulargewicht
- 79 kDa
- Gen-ID
- 11194
- NCBI Accession
- NM_007188, NP_009119
- UniProt
- Q9NUT2
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