ABCC1 Antikörper (Middle Region)
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- Target Alle ABCC1 Antikörper anzeigen
- ABCC1 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1))
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Bindungsspezifität
- Middle Region
- Reaktivität
- Human, Ratte, Rind (Kuh), Hund, Kaninchen, Schwein, Meerschweinchen, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ABCC1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- LFISFLSIFL FMCNHVSALA SNYWLSLWTD DPIVNGTQEH TKVRLSVYGA
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 77%, Horse: 92%, Human: 100%, Pig: 100%, Rabbit: 93%, Rat: 85%
- Produktmerkmale
- This is a rabbit polyclonal antibody against ABCC1. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human ABCC1
- Top Product
- Discover our top product ABCC1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 1531 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ABCC1 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1))
- Andere Bezeichnung
- ABCC1 (ABCC1 Produkte)
- Synonyme
- ABC29 antikoerper, ABCC antikoerper, GS-X antikoerper, MRP antikoerper, MRP1 antikoerper, Abcc1a antikoerper, Abcc1b antikoerper, Mdrap antikoerper, Mrp1 antikoerper, Avcc1a antikoerper, Mrp antikoerper, ABCC13 antikoerper, ATP binding cassette subfamily C member 1 antikoerper, ATP-binding cassette, sub-family C (CFTR/MRP), member 1 antikoerper, multidrug resistance-associated protein 1 antikoerper, ABCC1 antikoerper, Abcc1 antikoerper, LOC100152428 antikoerper, LOC100346553 antikoerper
- Hintergrund
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ABCC1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms.
Alias Symbols: ABC29, ABCC, DKFZp686N04233, DKFZp781G125, GS-X, MRP, MRP1
Protein Interaction Partner: UBC, ABCC1, CAV1, TRAF3, NPM1, AZGP1, STT3B, RAVER1, MCU, MRPL17, TMCO1, ATP6V1H, TMX2, TMOD2, NDUFAF3, FKBP8, PUF60, PGRMC2, FLOT1, PDCD6IP, ATP6V1F, EIF3C, PDHX, VDAC3, SURF1, STX4, SAFB, RPS7, NDUFB9, DBT, TMEM173, UNC93B1,
Protein Size: 1531 - Molekulargewicht
- 171 kDa
- Gen-ID
- 4363
- NCBI Accession
- NM_004996, NP_004987
- UniProt
- P33527
- Pathways
- SARS-CoV-2 Protein Interaktom
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