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KLHL3 Antikörper (N-Term)

KLHL3 Reaktivität: Human, Ratte, Rind (Kuh), Meerschweinchen, Hund, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2781023
  • Target Alle KLHL3 Antikörper anzeigen
    KLHL3 (Kelch-Like 3 (KLHL3))
    Bindungsspezifität
    • 15
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 50
    • 9
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Ratte, Rind (Kuh), Meerschweinchen, Hund, Kaninchen
    Wirt
    • 48
    • 2
    Kaninchen
    Klonalität
    • 50
    Polyklonal
    Konjugat
    • 22
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KLHL3 Antikörper ist unkonjugiert
    Applikation
    • 44
    • 24
    • 13
    • 13
    • 8
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    MEGESVKLSS QTLIQAGDDE KNQRTITVNP AHMGKAFKVM NELRSKQLLC
    Homologie
    Cow: 86%, Dog: 91%, Guinea Pig: 85%, Human: 100%, Rabbit: 100%, Rat: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against KLHL3. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human KLHL3
    Top Product
    Discover our top product KLHL3 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 587 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    KLHL3 (Kelch-Like 3 (KLHL3))
    Andere Bezeichnung
    KLHL3 (KLHL3 Produkte)
    Synonyme
    7530408C15Rik antikoerper, AI430941 antikoerper, EG627648 antikoerper, PHA2D antikoerper, RGD1565218 antikoerper, kelch like family member 3 antikoerper, kelch-like 3 antikoerper, kelch-like family member 3 antikoerper, KLHL3 antikoerper, Klhl3 antikoerper
    Hintergrund
    KLHL3 protein contains a poxvirus and zinc finger domain at the N-terminus and six tandem repeats (kelch repeats) at the C-terminus. At the amino acid level, KLHL3 shares 77 % similarity with Drosophila kelch and 89 % similarity with Mayven (KLHL2), another human kelch homolog. At least three isoforms are produced and may be the result of alternative promoter usage. The KLHL3 maps within the smallest commonly deleted segment in myeloid leukemias characterized by a deletion of 5q, however, no inactivating mutations of KLHL3 could be detected in malignant myeloid disorders with loss of 5q.
    Alias Symbols: PHA2D
    Protein Interaction Partner: WNK4, KLHL12, KLHL3, KEAP1, MORF4L2, CUL3, UBC, C6orf165, WNK3, WNK2, WNK1, RBX1, SLC12A3, ELAVL1, SYNCRIP, SYT2, OPRD1, GNAO1, GNAI1,
    Protein Size: 587
    Molekulargewicht
    65 kDa
    Gen-ID
    26249
    NCBI Accession
    NM_017415, NP_059111
    UniProt
    Q9UH77
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