MYST2 Antikörper (N-Term)

Produktnummer ABIN2780825

Produktdetails anti-MYST2 Antikörper

Target: MYST2 (MYST Histone Acetyltransferase 2 (MYST2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYST2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PRRKRNAGSS SDGTEDSDFS TDLEHTDSSE SDGTSRRSAR VTRSSARLSQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MYST2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MYST2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 611 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MYST2

Target: MYST2 (MYST Histone Acetyltransferase 2 (MYST2))

Andere Bezeichnung: MYST2 (MYST2 Produkte)

Synonyme: Myst2 antikoerper, HBO1 antikoerper, HBOA antikoerper, MYST2 antikoerper, ZC2HC7 antikoerper, Hbo1 antikoerper, Hboa antikoerper, lysine acetyltransferase 7 antikoerper, K(lysine) acetyltransferase 7 antikoerper, MYST histone acetyltransferase 2 antikoerper, Kat7 antikoerper, KAT7 antikoerper, myst2 antikoerper

Hintergrund: MYST2 belongs to the MYST family, which is characterized by a highly conserved C2HC zinc finger and a putative histone acetyltransferase domain. MYST2 specifically represses AR-mediated transcription. MYST2 is a new AR-interacting protein capable of modulating AR activity. It could play a significant role in regulating AR-dependent genes in normal and prostate cancer cells. The biochemical and genetic interactions of MYST family protein MYST2 with two components of the replication apparatus, MCM2 and ORC1, suggest that MYST2-associated HAT activity may play a direct role in the process of DNA replication. MYST2 is a positive regulatory factor for prereplicative complex assembly.
Alias Symbols: HBO1, HBOA, KAT7, MYST2
Protein Interaction Partner: UBC, RNF2, EZH2, VIM, CDK11B, APP, HAP1, BARD1, LRIF1, ING4, JADE1, CSNK1E, DYNC1I1, CDT1, tat, HIST1H4A, HIST1H3A, HIST2H2AC, GMNN, ORC2, MCM2, CDC6, JUN, KIAA1377, CEP70, CBX8, CAAP1, KCTD13, PPID, WDR33, NINL, ZBTB8B, HOOK2, KATNBL1, POLB, CALCOCO2, AT
Protein Size: 611

Molekulargewicht: 71 kDa

Gen-ID: 11143

NCBI Accession: NM_007067, NP_008998

UniProt: O95251