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NR1H3 Antikörper (C-Term)

NR1H3 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Ziege, Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2780709
  • Target Alle NR1H3 Antikörper anzeigen
    NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
    Bindungsspezifität
    • 16
    • 15
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 76
    • 55
    • 44
    • 17
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Ziege, Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)
    Wirt
    • 84
    • 9
    • 2
    Kaninchen
    Klonalität
    • 77
    • 18
    Polyklonal
    Konjugat
    • 43
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser NR1H3 Antikörper ist unkonjugiert
    Applikation
    • 81
    • 31
    • 27
    • 27
    • 27
    • 10
    • 10
    • 8
    • 8
    • 7
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    IHHPHDRLMF PRMLMKLVSL RTLSSVHSEQ VFALRLQDKK LPPLLSEIWD
    Homologie
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against NR1H3. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human NR1H3
    Top Product
    Discover our top product NR1H3 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 447 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Torra, Ismaili, Feig, Xu, Cavasotto, Pancratov, Rogatsky, Neubert, Fisher, Garabedian: "Phosphorylation of liver X receptor alpha selectively regulates target gene expression in macrophages." in: Molecular and cellular biology, Vol. 28, Issue 8, pp. 2626-36, (2008) (PubMed).

  • Target
    NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
    Andere Bezeichnung
    NR1H3 (NR1H3 Produkte)
    Synonyme
    NR1H3 antikoerper, LXR-a antikoerper, LXRA antikoerper, RLD-1 antikoerper, AU018371 antikoerper, LXR antikoerper, RLD1 antikoerper, Unr1 antikoerper, LXRalpha antikoerper, LXR-alpha antikoerper, im:7141239 antikoerper, wu:fd59b01 antikoerper, zgc:113339 antikoerper, zgc:158542 antikoerper, nuclear receptor subfamily 1 group H member 3 antikoerper, nuclear receptor subfamily 1, group H, member 3 antikoerper, NR1H3 antikoerper, nr1h3 antikoerper, Nr1h3 antikoerper
    Hintergrund
    Interaction of NR1H3 with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. NR1H3 are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. NR1H3 Plays an important role in the regulation of cholesterol homeostasis.
    Alias Symbols: LXR-a, LXRA, RLD-1
    Protein Interaction Partner: RXRG, RXRB, MDFI, SUV39H1, KDM1A, BARD1, MSTO1, HSP90AA1, PIAS1, APP, NR3C1, MYC, ZXDC, TMEM161A, ING3, NCOA6, NCOR1, KAT2B, EIF3I, NRIP1, NCOA3, SRC, RXRA, FOXO3, ACTN1, SS18L1, LZTR1, EDF1, RARA, NR0B2, SYT1, PPARA, SIRT1, UBC, CEP350,
    Protein Size: 447
    Molekulargewicht
    50 kDa
    Gen-ID
    10062
    NCBI Accession
    NM_005693, NP_005684
    UniProt
    Q13133
    Pathways
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding, Cellular Response to Molecule of Bacterial Origin, Hepatitis C
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