Splicing Factor 1 Antikörper (N-Term)

Produktnummer ABIN2780613

Produktdetails anti-Splicing Factor 1 Antikörper

Target: Splicing Factor 1 (SF1)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Splicing Factor 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ATGANATPLD FPSKKRKRSR WNQDTMEQKT VIPGMPTVIP PGLTREQERA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 75%

Produktmerkmale: This is a rabbit polyclonal antibody against SF1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SF1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 639 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Splicing Factor 1

Target: Splicing Factor 1 (SF1)

Andere Bezeichnung: SF1 (SF1 Produkte)

Synonyme: BBP antikoerper, D11S636 antikoerper, MBBP antikoerper, ZCCHC25 antikoerper, ZFM1 antikoerper, ZNF162 antikoerper, BB094781 antikoerper, CW17R antikoerper, MZFM antikoerper, WBP4 antikoerper, Zfp162 antikoerper, CG5836 antikoerper, Dmel\\CG5836 antikoerper, cg5836 antikoerper, dSF1 antikoerper, p70 antikoerper, SF1 antikoerper, sf1 antikoerper, wu:fc09f06 antikoerper, znf162 antikoerper, MWD22.25 antikoerper, MWD22_25 antikoerper, SF-1 antikoerper, splicing factor 1 antikoerper, Splicing factor 1 antikoerper, splicing factor-like protein antikoerper, nuclear receptor subfamily 5 group A member 1 antikoerper, splicing factor 1 S homeolog antikoerper, SF1 antikoerper, Sf1 antikoerper, sf1 antikoerper, AT5G51300 antikoerper, NR5A1 antikoerper, sf1.S antikoerper

Hintergrund: SF1 contains 1 CCHC-type zinc finger and 1 KH domain. SF1 is Necessary for the ATP-dependent first step of spliceosome assembly. It binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. SF1 may act as transcription repressor.
Alias Symbols: D11S636, ZFM1, ZNF162, BBP, MBBP
Protein Interaction Partner: KRTAP26-1, TRIM69, FAM168A, CIAO1, MKRN3, PSMA3, FUS, UBC, NEDD8, SUZ12, EED, RPL24, PLOD2, OSBP, NARS, GFPT1, GART, EIF4B, APBB1, SUPT5H, TROVE2, ITCH, PRPF40A, SAMHD1, XPO7, WBP4, FAF1, TCERG1, HSPH1, FARSB, GAS7, RANBP3, HIRIP3, HIST1H4A, XRCC5, U2AF2,
Protein Size: 639

Molekulargewicht: 68 kDa

Gen-ID: 7536

NCBI Accession: NM_004630, NP_004621

UniProt: Q15637

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Maintenance of Protein Location