EZH2 Antikörper (N-Term)

Produktnummer ABIN2780595

Produktdetails anti-EZH2 Antikörper

Target: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Zebrafisch (Danio rerio), Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EZH2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: KGPVCWRKRV KSEYMRLRQL KRFRRADEVK SMFSSNRQKI LERTEILNQE

Spezifität: From peptide immunogen, will recognize all 5 isoforms.

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against EZH2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EZH2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 751 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EZH2

Target: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Andere Bezeichnung: EZH2 (EZH2 Produkte)

Synonyme: ENX-1 antikoerper, ENX1 antikoerper, EZH1 antikoerper, EZH2b antikoerper, KMT6 antikoerper, KMT6A antikoerper, WVS antikoerper, WVS2 antikoerper, eya2 antikoerper, im:7149338 antikoerper, zgc:136376 antikoerper, zgc:152758 antikoerper, EZH2 antikoerper, enx-1 antikoerper, enx1 antikoerper, ezh1 antikoerper, kmt6 antikoerper, xez antikoerper, Enx-1 antikoerper, Enx1h antikoerper, mKIAA4065 antikoerper, ezh2 antikoerper, olezh2 antikoerper, enhancer of zeste 2 polycomb repressive complex 2 subunit antikoerper, enhancer of zeste 2 polycomb repressive complex 2 subunit L homeolog antikoerper, enhancer of zeste 2 polycomb repressive complex 2 subunit S homeolog antikoerper, EZH2 antikoerper, ezh2 antikoerper, Ezh2 antikoerper, ezh2.L antikoerper, ezh2.S antikoerper

Hintergrund: EZH2 is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems.
Alias Symbols: ENX1, EZH1, KMT6, WVS2, ENX-1, KMT6A
Protein Interaction Partner: FBXW11, CEP63, HOTAIR, EED, BRCA1, SUZ12, SNAI1, SRSF1, SDCBP, UPF1, RBBP7, RBBP4, RAP1GAP, PLEC, PKM, POTEE, DHX36, AEBP2, HIST4H4, KLC4, SERPINB12, PHF5A, FIP1L1, FBXL18, CPSF7, DDX3X, DBN1, SLC25A10, COPB1, CALML3, ATP5C1, ATP5B, ATP2A2, ARG1, AR, ANXA
Protein Size: 751

Molekulargewicht: 85 kDa

Gen-ID: 2146

NCBI Accession: NM_001203247, NP_004447

UniProt: Q15910

Pathways: Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation