SOX4 (N-Term) Antikörper

Details zu Produkt Nr. ABIN2780469, Anbieter: Anmelden zum Anzeigen
Antigen
  • EVI16
  • AA682046
  • Sox-4
  • sox4
  • wu:fb82f08
  • wu:fq41g10
  • zgc:65850
  • zgc:77392
  • SRY-box 4
  • SRY box 4
  • SRY (sex determining region Y)-box 4
  • SRY (sex determining region Y)-box 4a
  • SOX4
  • Sox4
  • sox4a
Epitop
N-Term
23
8
5
5
5
4
4
2
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch (Danio rerio)
77
27
24
4
4
2
2
1
1
1
1
Wirt
Kaninchen
63
14
Klonalität
Polyklonal
Konjugat
Unkonjugiert
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
41
27
18
14
13
12
6
5
3
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human SOX4
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN984276.
Sequenz STASTGGKAD DPSWCKTPSG HIKRPMNAFM VWSQIERRKI MEQSPDMHNA
Spezifität Peptide immunogen shares 93 % with human SOX11.
Homologie Cow: 100%, Dog: 100%, Goat: 91%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
Produktmerkmale This is a rabbit polyclonal antibody against SOX4. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Hintergrund SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. It may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: EVI16
Protein Interaction Partner: TAF5, UBE2I, ELAVL1, TP53, MDM2, EP300, tat, SDCBP,
Protein Size: 474
Molekulargewicht 47 kDa
Gen-ID 6659
NCBI Accession NM_003107, NP_003098
UniProt Q06945
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 474 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-SOX4 (N-Term) antibody (ABIN2780469) anti-SOX4 (N-Term) antibody
Immunohistochemistry (IHC) image for anti-SOX4 (N-Term) antibody (ABIN2780469) anti-SOX4 (N-Term) antibody (Image 2)
Western Blotting (WB) image for anti-SOX4 (N-Term) antibody (ABIN2780469) Host: Rabbit
Target Name: SOX4
Sample Tissue: Human Fetal Heart
...
Western Blotting (WB) image for anti-SOX4 (N-Term) antibody (ABIN2780469) Host: Rabbit
Target Name: SOX4
Sample Tissue: Human Fetal Liver
...
Immunohistochemistry (IHC) image for anti-SOX4 (N-Term) antibody (ABIN2780469) Human Heart
Immunohistochemistry (IHC) image for anti-SOX4 (N-Term) antibody (ABIN2780469) Human Testis
Allgemeine Veröffentlichungen Hoser, Baader, Bösl, Ihmer, Wegner, Sock: "Prolonged glial expression of Sox4 in the CNS leads to architectural cerebellar defects and ataxia." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 20, pp. 5495-505, 2007 (PubMed).

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