RFX1 Antikörper (Middle Region)

Produktnummer ABIN2780454

Produktdetails anti-RFX1 Antikörper

Target: RFX1 (Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RFX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EDTDLSRLYT ATSLMQIDDN VMRKFHGYNS LKEYYEEESC MRYLHRIYVP

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 90%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RFX1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RFX1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 979 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RFX1

Target: RFX1 (Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1))

Andere Bezeichnung: RFX1 (RFX1 Produkte)

Synonyme: EFC antikoerper, RFX antikoerper, AI047719 antikoerper, AI385641 antikoerper, zgc:162914 antikoerper, regulatory factor X1 antikoerper, regulatory factor X, 1 (influences HLA class II expression) antikoerper, regulatory factor X, 1a (influences HLA class II expression) antikoerper, RFX1 antikoerper, Rfx1 antikoerper, rfx1a antikoerper

Hintergrund: RFX1 is a member of the regulatory factor X protein family, which are transcription factors that contain a highly-conserved winged helix DNA binding domain. RFX1 is structurally related to regulatory factors X2, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with RFX family members X2, X3, and X5, but not with X4. This protein binds to the X-boxes of MHC class II genes and is essential for their expression. Also, it can bind to an inverted repeat that is required for expression of hepatitis B virus genes. This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X2, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with RFX family members X2, X3, and X5, but not with X4. This protein binds to the X-boxes of MHC class II genes and is essential for their expression. Also, it can bind to an inverted repeat that is required for expression of hepatitis B virus genes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: EF-C, EFC, RFX
Protein Interaction Partner: SOX2, SMAD9, SMAD4, SMAD1, NOTCH1, Cebpb, NCOA3, HDAC1, NFIC, NFIB, TADA3, RFX3, MAGED1, ABL1, NFIX, HMGB1, HIVEP2, RFX2, ADD1,
Protein Size: 979

Molekulargewicht: 105 kDa

Gen-ID: 5989

NCBI Accession: NM_002918, NP_002909

UniProt: P22670