PITX2 Antikörper (N-Term)
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- Target Alle PITX2 Antikörper anzeigen
- PITX2 (Paired-Like Homeodomain 2 (PITX2))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Ratte, Maus, Schwein, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PITX2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- EHRAAGTKLS AVSSSSCHHP QPLAMASVLA PGQPRSLDSS KHRLEVHTIS
- Homologie
- Human: 100%, Mouse: 92%, Pig: 92%, Rabbit: 92%, Rat: 92%
- Produktmerkmale
- This is a rabbit polyclonal antibody against PITX2. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product PITX2 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 324 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PITX2 (Paired-Like Homeodomain 2 (PITX2))
- Andere Bezeichnung
- PITX2 (PITX2 Produkte)
- Synonyme
- ARP1 antikoerper, Brx1 antikoerper, IDG2 antikoerper, IGDS antikoerper, IGDS2 antikoerper, IHG2 antikoerper, IRID2 antikoerper, Otlx2 antikoerper, PTX2 antikoerper, RGS antikoerper, RIEG antikoerper, RIEG1 antikoerper, RS antikoerper, 9430085M16Rik antikoerper, Brx1a antikoerper, Brx1b antikoerper, Munc30 antikoerper, Pitx2a antikoerper, Pitx2b antikoerper, Pitx2c antikoerper, Pitx2cbeta antikoerper, Ptx2 antikoerper, Rieg antikoerper, pitx2a antikoerper, pitx2c antikoerper, zgc:110508 antikoerper, XPtx2b antikoerper, xPtx2 antikoerper, xpitx2 antikoerper, arp1 antikoerper, brx1 antikoerper, idg2 antikoerper, igds antikoerper, igds2 antikoerper, ihg2 antikoerper, irid2 antikoerper, otlx2 antikoerper, pitx2-A antikoerper, ptx2 antikoerper, rgs antikoerper, rieg antikoerper, rieg1 antikoerper, pitx-2 antikoerper, pitx2 antikoerper, paired like homeodomain 2 antikoerper, paired-like homeodomain transcription factor 2 antikoerper, paired-like homeodomain 2 antikoerper, paired like homeodomain 2 S homeolog antikoerper, paired like homeodomain 2 L homeolog antikoerper, PITX2 antikoerper, Pitx2 antikoerper, pitx2 antikoerper, pitx2.S antikoerper, pitx2.L antikoerper
- Hintergrund
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This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Alias Symbols: ARP1, Brx1, IDG2, IGDS, IGDS2, IHG2, IRID2, MGC111022, MGC20144, Otlx2, PTX2, RGS, RIEG, RIEG1, RS
Protein Interaction Partner: LEF1, Hoxa1, WDR5, SMAD3, HDAC1, CTNNB1, ZNHIT3, TRIM25, HERC5, PDLIM1, PITX2, PROP1, KAT5, Pou1f1, MSX2,
Protein Size: 324 - Molekulargewicht
- 36 kDa
- Gen-ID
- 5308
- NCBI Accession
- NM_000325, NP_000316
- Pathways
- Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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