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ERCC6 Antikörper (C-Term)

ERCC6 Reaktivität: Human, Ratte, Maus, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2780327
  • Target Alle ERCC6 Antikörper anzeigen
    ERCC6 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6))
    Bindungsspezifität
    • 15
    • 10
    • 8
    • 6
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    Human, Ratte, Maus, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)
    Wirt
    • 43
    • 4
    • 1
    Kaninchen
    Klonalität
    • 45
    • 3
    Polyklonal
    Konjugat
    • 24
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ERCC6 Antikörper ist unkonjugiert
    Applikation
    • 41
    • 22
    • 13
    • 13
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequenz
    EASALLPTTE HDDLLVEMRN FIAFQAHTDG QASTREILQE FESKLSASQS
    Homologie
    Cow: 86%, Dog: 79%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 86%, Zebrafish: 79%
    Produktmerkmale
    This is a rabbit polyclonal antibody against ERCC6. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C-terminal region of human ERCC6
    Top Product
    Discover our top product ERCC6 Primärantikörper
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeat freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    ERCC6 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6))
    Andere Bezeichnung
    ERCC6 (ERCC6 Produkte)
    Synonyme
    ARMD5 antikoerper, CKN2 antikoerper, COFS antikoerper, COFS1 antikoerper, CSB antikoerper, RAD26 antikoerper, UVSS1 antikoerper, 4732403I04 antikoerper, C130058G22Rik antikoerper, ercc6 antikoerper, Ercc6 antikoerper, ERCC excision repair 6, chromatin remodeling factor antikoerper, excision repair cross-complementing rodent repair deficiency, complementation group 6 antikoerper, excision repair cross-complementation group 6 antikoerper, DNA excision repair protein ERCC-6 antikoerper, ERCC6 antikoerper, Ercc6 antikoerper, ercc6 antikoerper, LOC100719487 antikoerper
    Hintergrund
    This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The encoded protein has ATP-stimulated ATPase activity, interacts with several transcription and excision repair proteins, and may promote complex formation at DNA repair sites. Mutations in this gene are associated with Cockayne syndrome type B and cerebrooculofacioskeletal syndrome 1. Naturally-occurring readthrough transcription occurs between this gene and the adjacent PGBD3 gene (GeneID:267004), and results in a fusion protein that shares sequence with the product of each individual gene. The readthrough locus is represented by GeneID:101243544.
    Alias Symbols: CSB, CKN2, COFS, ARMD5, COFS1, RAD26, UVSS1
    Protein Size: 863
    Molekulargewicht
    94 kDa
    Gen-ID
    2074
    NCBI Accession
    NM_000124, NP_000115
    UniProt
    Q03468
    Pathways
    DNA Reparatur, Chromatin Binding
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