KCNMA1 Antikörper (Middle Region)

Produktnummer ABIN2780204

Produktdetails anti-KCNMA1 Antikörper

Target: KCNMA1 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Zebrafisch (Danio rerio), Kaninchen, Hund, Pferd, Schaf, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNMA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ESRSRKRILI NPGNHLKIQE GTLGFFIASD AKEVKRAFFY CKACHDDITD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against KCNMA1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KCNMA1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1182 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu KCNMA1

Target: KCNMA1 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1))

Andere Bezeichnung: KCNMA1 (KCNMA1 Produkte)

Synonyme: BKTM antikoerper, KCa1.1 antikoerper, MaxiK antikoerper, SAKCA antikoerper, SLO antikoerper, SLO-ALPHA antikoerper, SLO1 antikoerper, bA205K10.1 antikoerper, mSLO1 antikoerper, DDBDRAFT_0190653 antikoerper, DDBDRAFT_0235401 antikoerper, DDB_0190653 antikoerper, DDB_0235401 antikoerper, KCNMA antikoerper, KCNMA1 antikoerper, 5730414M22Rik antikoerper, BKCa antikoerper, Slo antikoerper, Slo1 antikoerper, mSlo antikoerper, mSlo1 antikoerper, KCNMA1b antikoerper, KCNMA1c antikoerper, Kcnma antikoerper, bktm antikoerper, kcnma1-A antikoerper, sakca antikoerper, cSlo antikoerper, slo1 antikoerper, kcnma1 antikoerper, si:ch211-39f22.2 antikoerper, BcDNA:GH10751 antikoerper, CG10693 antikoerper, Dmel\CG10693 antikoerper, Dslo antikoerper, dSlo antikoerper, dSlo1 antikoerper, dslo antikoerper, fSlo antikoerper, potassium calcium-activated channel subfamily M alpha 1 antikoerper, calcium-activated BK potassium channel, alpha subunit antikoerper, potassium large conductance calcium-activated channel, subfamily M, alpha member 1 antikoerper, potassium calcium-activated channel subfamily M alpha 1 L homeolog antikoerper, potassium large conductance calcium-activated channel, subfamily M, alpha member 1a antikoerper, calcium-activated potassium channel subunit alpha-1 antikoerper, slowpoke antikoerper, KCNMA1 antikoerper, kcnma1 antikoerper, Kcnma1 antikoerper, kcnma1.L antikoerper, kcnma1a antikoerper, LOC100454095 antikoerper, slo antikoerper

Hintergrund: This protein is a transcription factor that interacts with specific negative regulatory elements (NREs) to mediate transcriptional repression of certain NK-kappa-B-responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm.MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: BKTM, DKFZp686K1437, KCa1.1, MGC71881, MaxiK, SAKCA, SLO, SLO-ALPHA, mSLO1, SLO1, bA205K10.1
Protein Interaction Partner: EED, TBXA2R, KCNMB1, KCNMA1, CAV3, CAV2, CAV1, ACTG2, ACTA2, ALB, CACNA1H, PTK2, MAP1A, GGT1, HMOX2,
Protein Size: 1182

Molekulargewicht: 131 kDa

Gen-ID: 3778

NCBI Accession: NM_001014797, NP_001014797

UniProt: Q12791

Pathways: Regulation of Hormone Metabolic Process, Sensory Perception of Sound