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MAFA Antikörper (Middle Region)

MAFA Reaktivität: Maus, Ratte, Rind (Kuh) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2780174
  • Target Alle MAFA Antikörper anzeigen
    MAFA (Transcription Factor MafA (MAFA))
    Bindungsspezifität
    • 12
    • 7
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 49
    • 32
    • 22
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus, Ratte, Rind (Kuh)
    Wirt
    • 51
    • 3
    Kaninchen
    Klonalität
    • 51
    • 3
    Polyklonal
    Konjugat
    • 30
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MAFA Antikörper ist unkonjugiert
    Applikation
    • 50
    • 20
    • 12
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    GGGSAAQAGG APGPPSGGPG TVGGASGKAV LEDLYWMSGY QHHLNPEALN
    Homologie
    Cow: 79%, Mouse: 100%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against Mafa. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide corresponding to a region of Mouse
    Top Product
    Discover our top product MAFA Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 359 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    MAFA (Transcription Factor MafA (MAFA))
    Andere Bezeichnung
    Mafa (MAFA Produkte)
    Synonyme
    RIPE3b1 antikoerper, hMafA antikoerper, RGD1562627 antikoerper, 2F1-Ag antikoerper, MAFA antikoerper, MAFA-L antikoerper, SMaf1 antikoerper, mafl antikoerper, L-MAF antikoerper, MAFL antikoerper, Maf antikoerper, v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian) antikoerper, MAF bZIP transcription factor A antikoerper, killer cell lectin-like receptor subfamily G, member 1 antikoerper, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A antikoerper, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Aa antikoerper, monocyte to macrophage differentiation-associated antikoerper, Mafa antikoerper, MAFA antikoerper, Klrg1 antikoerper, mafa antikoerper, mafaa antikoerper, Mmd antikoerper
    Hintergrund
    Mafa acts as a transcriptional factor. Mafa specifically binds the insulin enhancer element RIPE3b. Mafa cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity. Mafa regulates the insulin gene transcription. Mafa is involved either as an oncogene or as a tumor suppressor, depending on the cell context.
    Alias Symbols: RIPE3b1
    Protein Interaction Partner: Psme3,
    Protein Size: 359
    Molekulargewicht
    37 kDa
    Gen-ID
    378435
    NCBI Accession
    NM_194350, NP_919331
    UniProt
    Q8CF90
    Pathways
    Hormone Transport
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