NFAT1 Antikörper (N-Term)

Produktnummer ABIN2779960

Produktdetails anti-NFAT1 Antikörper

Target: NFAT1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFAT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MDVPEPQPDP DGGDGPGHEP GGSPQDELDF SILFDYDYLN PIEEEPIAHK

Homologie: Cow: 86%, Dog: 82%, Horse: 93%, Human: 93%, Mouse: 100%, Pig: 79%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against NFATC2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of mouse NFATC2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 927 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-NFAT1 Antikörper (ABIN2779960)

Nagamoto-Combs, Combs: "Microglial phenotype is regulated by activity of the transcription factor, NFAT (nuclear factor of activated T cells)." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 28, pp. 9641-6, (2010) (PubMed).

Heer, Clarke, Rigas, Cheek, Pickard, Leung: "Phenotypic modulation of human urinary tract stroma-derived fibroblasts by transforming growth factor beta3." in: Urology, Vol. 76, Issue 2, pp. 509.e13-20, (2010) (PubMed).

Details zu NFAT1

Target: NFAT1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))

Andere Bezeichnung: NFATC2 (NFAT1 Produkte)

Synonyme: NFATC2 antikoerper, AI607462 antikoerper, NF-ATc2 antikoerper, NFAT1 antikoerper, NFAT1-D antikoerper, Nfatp antikoerper, NFATP antikoerper, nuclear factor of activated T-cells 2 antikoerper, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 antikoerper, NFATC2 antikoerper, nfatc2 antikoerper, Nfatc2 antikoerper

Hintergrund: NFATC2 is a member of The NF-AT family of potent transcription factors that are essential for T cell activation
Alias Symbols: NFAT1, Nfatp, NF-ATc2, NFAT1-D, AI607462
Protein Interaction Partner: Foxp3, Il4, Ifng, Nfatc2ip,
Protein Size: 927

Molekulargewicht: 100 kDa

Gen-ID: 18019

NCBI Accession: NM_010899, NP_035029

Pathways: RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, VEGF Signaling, BCR Signaling