TAF5L Antikörper (N-Term)

Produktnummer ABIN2779727

Produktdetails anti-TAF5L Antikörper

Target: TAF5L (TAF5-Like RNA Polymerase II, P300/CBP-Associated Factor (PCAF)-Associated Factor, 65kDa (TAF5L))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Hund, Ratte, Kaninchen, Meerschweinchen, Pferd, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TAF5L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: LTDSDSQHSH EVMPLLYPLF VYLHLNLVQN SPKSTVESFY SRFHGMFLQN

Homologie: Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against TAF5L. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TAF5L

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 589 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TAF5L

Target: TAF5L (TAF5-Like RNA Polymerase II, P300/CBP-Associated Factor (PCAF)-Associated Factor, 65kDa (TAF5L))

Andere Bezeichnung: TAF5L (TAF5L Produkte)

Synonyme: PAF65B antikoerper, taf5l antikoerper, MGC89568 antikoerper, fi28g02 antikoerper, wu:fi28g02 antikoerper, zgc:63765 antikoerper, 1110005N04Rik antikoerper, AI849020 antikoerper, TATA-box binding protein associated factor 5 like antikoerper, TATA-box binding protein associated factor 5 like L homeolog antikoerper, PCAF associated factor 65 beta antikoerper, TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor antikoerper, TAF5L antikoerper, taf5l.L antikoerper, taf5l antikoerper, PY07202 antikoerper, Taf5l antikoerper

Hintergrund: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF5L encodes a protein that is a component of the PCAF histone acetylase complex and structurally similar to one of the histone-like TAFs, TAF5. The PCAF histone acetylase complex, which is composed of more than 20 polypeptides some of which are TAFs, is required for myogenic transcription and differentiation.
Alias Symbols: PAF65B
Protein Interaction Partner: HECW2, UBC, KAT2B, LSM11, TADA3, TAF10, ELAVL1, TSC22D1, TTR, H2AFX, CDKN1A, ANXA7, KAT2A, TP53, ATXN7, CEBPE, USP22, ATXN7L3, SUPT3H, TAF9, MYC,
Protein Size: 589

Molekulargewicht: 66 kDa

Gen-ID: 27097

NCBI Accession: NM_014409, NP_055224

UniProt: O75529