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NR5A2 + LRH1 Antikörper (Middle Region)

NR5A2 Reaktivität: Human, Ratte, Maus, Rind (Kuh), Meerschweinchen, Schaf, Hund, Pferd, Zebrafisch (Danio rerio), Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2779697
  • Target Alle NR5A2 + LRH1 (NR5A2) Antikörper anzeigen
    NR5A2 + LRH1 (NR5A2) (Nuclear Receptor Subfamily 5, Group A, Member 2 (NR5A2))
    Bindungsspezifität
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 46
    • 21
    • 18
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Human, Ratte, Maus, Rind (Kuh), Meerschweinchen, Schaf, Hund, Pferd, Zebrafisch (Danio rerio), Kaninchen
    Wirt
    • 43
    • 5
    • 2
    Kaninchen
    Klonalität
    • 45
    • 5
    Polyklonal
    Konjugat
    • 34
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NR5A2 + LRH1 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 17
    • 13
    • 6
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB)
    Sequenz
    LPPTDYDRSP FVTSPISMTM LHGSLQGYQT YGHFPSRAIK SEYPDPYTSS
    Homologie
    Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Sheep: 86%, Zebrafish: 79%
    Produktmerkmale
    This is a rabbit polyclonal antibody against NR5A2. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human NR5A2
    Top Product
    Discover our top product NR5A2 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 323 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    NR5A2 + LRH1 (NR5A2) (Nuclear Receptor Subfamily 5, Group A, Member 2 (NR5A2))
    Andere Bezeichnung
    NR5A2 (NR5A2 Produkte)
    Synonyme
    xff1rashort antikoerper, NR5A2 antikoerper, b1f antikoerper, b1f2 antikoerper, cpf antikoerper, ff1r antikoerper, ftf antikoerper, ftz-f1 antikoerper, ftz-f1beta antikoerper, hb1f antikoerper, hb1f-2 antikoerper, lrh-1 antikoerper, lrh1 antikoerper, xff1ra antikoerper, B1F antikoerper, B1F2 antikoerper, CPF antikoerper, FTF antikoerper, FTZ-F1 antikoerper, FTZ-F1beta antikoerper, LRH-1 antikoerper, LRH1 antikoerper, hB1F-2 antikoerper, xFF1rB antikoerper, AU020803 antikoerper, D1Ertd308e antikoerper, Ftf antikoerper, UF2-H3B antikoerper, Lrh-1 antikoerper, nuclear receptor subfamily 5 group A member 2 S homeolog antikoerper, nuclear receptor subfamily 5 group A member 2 antikoerper, nuclear receptor subfamily 5 group A member 2 L homeolog antikoerper, nuclear receptor subfamily 5, group A, member 2 antikoerper, nr5a2.S antikoerper, NR5A2 antikoerper, nr5a2 antikoerper, nr5a2.L antikoerper, Nr5a2 antikoerper
    Hintergrund
    NR5A2 binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. It may be responsable for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. It is a key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. It may also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.
    Alias Symbols: B1F, B1F2, CPF, FTF, FTZ-F1, FTZ-F1beta, LRH-1, hB1F, hB1F-2, LRH1
    Protein Interaction Partner: NSD1, NCOA1, CREB1, UBE2I, RAD54L2, NR0B2, GPS2, ILF3, PNRC2, COPS5, PNRC1, BCKDK, NRIP1, SRC, NPPA, FTH1, ALB, SUMO1, PPARGC1A, POLR2D, EDF1, SMARCD3, PROX1, Ncoa3, Ptpn6, CTNNB1,
    Protein Size: 323
    Molekulargewicht
    36 kDa
    Gen-ID
    2494
    NCBI Accession
    NM_003822
    UniProt
    O60587
    Pathways
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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