BAD Antikörper (C-Term)
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- Target Alle BAD Antikörper anzeigen
- BAD (BCL2-Associated Agonist of Cell Death (BAD))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser BAD Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- RMSDEFVDSF KKGLPRPKSA GTATQMRQSS SWTRVFQSWW DRNLGRGSSA
- Homologie
- Cow: 100%, Dog: 90%, Guinea Pig: 100%, Horse: 90%, Human: 100%, Mouse: 100%, Pig: 90%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against BAD. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human BAD
- Top Product
- Discover our top product BAD Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 168 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- BAD (BCL2-Associated Agonist of Cell Death (BAD))
- Andere Bezeichnung
- BAD (BAD Produkte)
- Synonyme
- bad antikoerper, fa01b12 antikoerper, wu:fa01b12 antikoerper, wu:fa96d04 antikoerper, BAD antikoerper, BBC2 antikoerper, BCL2L8 antikoerper, AI325008 antikoerper, Bbc2 antikoerper, BCL2-associated agonist of cell death b antikoerper, BCL2 associated agonist of cell death antikoerper, BCL2-associated agonist of cell death antikoerper, badb antikoerper, BAD antikoerper, Bad antikoerper
- Hintergrund
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BAD is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Alias Symbols: BBC2, BCL2L8
Protein Interaction Partner: BCL2L1, BCL2, AKT1, PAK1, BMH1, YWHAB, SFN, YWHAZ, RAF1, PRKACA, BRAF, ARAF, CREB3L3, STEAP3, YWHAQ, KEAP1, YWHAH, YWHAE, PRDX2, CDKN1A, VCP, SNCA, PPP1CA, BAX, SUMO2, YWHAG, PIM3, MCL1, RPS6KA5, PAK7, BCL2L10, WASF1, HRK, MAP2K5, BCL2L2, RPS6KA2, RPS6KA1
Protein Size: 168 - Molekulargewicht
- 18 kDa
- Gen-ID
- 572
- NCBI Accession
- NM_004322, NP_004313
- UniProt
- Q92934
- Pathways
- MAPK Signalweg, PI3K-Akt Signalweg, RTK Signalweg, Apoptose, Fc-epsilon Rezeptor Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events
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